Skip to main content
SpringerLink
Log in

A new isocoumarin from mangrove endophytic fungus (No. dz17) on the South China Sea coast

  • Published:
Chemistry of Natural Compounds Aims and scope

Abstract

A new isocoumarin, 3,4-dihydro-6-methoxy-8-hydroxy-3,4,5-trimethylisocoumarin-7-carboxylic acid methyl ester (1), together with three known compounds, 3,4-dihydro-4,8-dihydroxy-3,5-dimethylisocoumarin (2), 3,4-dihydro-8-hydroxy-3-methylisocoumarin-5-carboxylic acid (3), and Entinclole SB (4) were isolated from the mangrove endophytic fungus (No. dz17). The structure of the compound 1 was elucidated by analysis of spectroscopic data. Primary bioassays showed that 1 exhibited weak cytotoxicity against Hep-2 and HepG2 cells.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. T. S. Bugni and C. M. Ireland, Nat. Prod. Rep., 21, 143 (2004).

    Article  PubMed  CAS  Google Scholar 

  2. G. Y. Chen, Y. C. Lin, L. Wen, L. L. P. Vrijmoed, and E. B. G. Jones, Tetrahedron, 59, 4907 (2003).

    Article  CAS  Google Scholar 

  3. Y. C. Lin, H. J. Li, G. C. Jiang, S. N. Zhou, L. L. P. Vrijmoed, and E. B. G. Jones, Indian. J. Chem., Sect. B, 41B, 1542 (2002).

    CAS  Google Scholar 

  4. Y. C. Lin, X. Y. Wu, Z. J. Deng, J. Wang, S. N. Zhou, L. L. P. Vrijmoed, and E. B. G. Jones, Phytochemistry, 59, 469 (2002).

    Article  PubMed  CAS  Google Scholar 

  5. Y. C. Lin, X. Y. Wu, S. Feng, G. C. Jiang, J. H. Luo, S. N. Zhou, L. L. P. Vrijmoed, E. B. G. Jones, K. Krohn, K. Steingroever, and F. Zsila, J. Org. Chem., 66, 6252 (2001).

    Article  PubMed  CAS  Google Scholar 

  6. Y. C. Lin, J. Wang, X. Y. Wu, S. N. Zhou, L. L. P. Vrijmoed, and E. B. G. Jones, Aust. J. Chem., 55, 225 (2002).

    Article  CAS  Google Scholar 

  7. Y. C. Lin, X. Y. Wu, S. Feng, G. C. Jiang, J. H. Luo, S. N. Zhou, L. L. P. Vrijmoed, and E. B. G. Jones, Tetrahedron Lett., 42, 449 (2001).

    Article  CAS  Google Scholar 

  8. K. Nozavva, S. Nakajima, and K. Kavva, J. Chem. Soc. Perkin Trans. I, 2607 (1988).

  9. H. J. Li, Y. C. Lin, L. Wang, S. N. Zhou, and L. L. P. Vrijmoed, Acta Scientiarum Naturalum Universitatis Sunyatseni, 40, 70 (2001).

    Google Scholar 

  10. I. Camby, I. Salmon, A. Danguy, J. L. Pasteels, J. Brotchi, and J. Martinez, J. Natl. Cancer. Inst., 88, 594 (1996).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. College of Chemistry and Chemical Engineering, Sun Yat-Sen (Zhongshan) University, 510275, Guangzhou, P.R. China

    Zhongjing Huang, Changlun Shao, Yiguang Chen, Zhigang She & Yongcheng Lin

  2. College of Life Science, Sun Yat-Sen (Zhongshan) University, 510275, Guangzhou, P.R. China

    Shining Zhou

Authors
  1. Zhongjing Huang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Changlun Shao
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yiguang Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Zhigang She
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Yongcheng Lin
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Shining Zhou
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yongcheng Lin.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 6, pp. 543–545, November–December, 2007.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Huang, Z., Shao, C., Chen, Y. et al. A new isocoumarin from mangrove endophytic fungus (No. dz17) on the South China Sea coast. Chem Nat Compd 43, 655–658 (2007). https://doi.org/10.1007/s10600-007-0221-z

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10600-007-0221-z

Key words

Search

Navigation