Skip to main content
SpringerLink
Log in

Isolation of lappaconitine from Aconitum septentrionale roots by adsorption

  • Published:
Chemistry of Natural Compounds Aims and scope

Abstract

Extracts of Aconitum septentrionale Koelle roots obtained using chloroform, isopropanol, and ethanol were purified using chloroform and basic γ-Al2O3. Ballast materials were selectively adsorbed by γ-Al2O3, increasing the mass fraction of lappaconitine in the extract. The ethanol extract was purified most. The degree of lappaconitine extraction by chloroform was unaffected by the presence of γ-Al2O3. However, the mass fraction in the extract and lappaconitine extraction from Aconitum septentrionale were increased more than twice.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. M. S. Yunusov, Bashk. Khim. Zh., 4, 4, 16 (1997).

    Google Scholar 

  2. H. Chiao, S. W. Pelletier, H. K. Desai, W. R. Rebagai, and R. W. Caldwell, Eur. J. Pharmacol., 283, 103 (1995).

    Article  PubMed  CAS  Google Scholar 

  3. A. D. Kuzovkov and P. S. Massagetov, Zh. Obshch. Khim., 25, 1, 178 (1955).

    Google Scholar 

  4. A. N. Manukov, Z. M. Vaisov, O. N. Denisenko, and V. A. Chelombit’ko, Khim. Prir. Soedin., 864 (1991).

  5. L. Marion, L. Fonzes, C. K. Wilkins, Jr., J. P. Boca, F. Sandberg, R. Thorsen, and E. Linden, Can. J. Chem., 45, 9, 969 (1967).

    Article  Google Scholar 

  6. M. S. Yunusov, E. M. Tsyrlina, S. G. Yunusova, V. A. Dokichev, A. N. Savenko, N. N. Istomin, A. I. Lishtakov, and A. A. Galyautdinov, Russ. Pat. No. 2,123,347 C1(1998).

  7. S. A. Ross and S. W. Pelletier, Tetrahedron, 48, 7, 1183 (1992).

    Article  Google Scholar 

  8. L. V. Beshitashvili, Khim. Prir. Soedin., 816 (1991).

  9. N. A. Pankrushina, O. I. Lomovskii, E. E. Shul’ts, E. Yu. Vinokurova, G. A. Tolstikov, and V. V. Boldyrev, Russ. Pat. No. 2,176,919 C2 (1999).

  10. O. I. Lomovskii, N. A. Pankrushina, E. A. Paukshtis, E. Yu. Khanukaeva, and E. Yu. Belyaev, Search, Development and Incorporation of New Medicinal Preparations and Organized Forms of Pharmaceutical Activity [in Russian], Tomsk (2000), p. 227.

  11. A. W. Adamson, Physical Chemistry of Surfaces, 3rd Ed., John Wiley & Sons, Chichester, Engl. (1976).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Novosibirsk State University, 630090, Novosibirsk, ul. Pirogova, 2

    A. E. Goncharov

  2. Institute of Solid-State and Mechanical Chemistry, Siberian Division, Russian Academy of Sciences, 630128, Novosibirsk, ul. Kutatelazde, 18

    A. A. Politov & O. I. Lomovskii

  3. Institute of Organic Chemistry, Siberian Division, Russian Academy of Sciences, 630090, Novosibirsk, ul. Lavrent’eva, 9

    N. A. Pankrushina

Authors
  1. A. E. Goncharov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. A. Politov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. A. Pankrushina
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. O. I. Lomovskii
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

__________

Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 274–276, May–June, 2006.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Goncharov, A.E., Politov, A.A., Pankrushina, N.A. et al. Isolation of lappaconitine from Aconitum septentrionale roots by adsorption. Chem Nat Compd 42, 336–339 (2006). https://doi.org/10.1007/s10600-006-0114-6

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10600-006-0114-6

Key words

Search

Navigation