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Chemo- and regioselective oxidation of substituted 2,3,4,9-tetrahydro-1H-carbazoles

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Chemistry of Heterocyclic Compounds Aims and scope

Chemo- and regioselective oxidation of substituted 2,3,4,9-tetrahydro-1H-carbazoles was used to obtain 2,3,4,9-tetrahydro-1H-carbazol-1-ones or 3,4,5,6-tetrahydro-1H-1-benzazonine-2,7-diones depending on the nature of the selected oxidant. In the case of benzo-fused tetrahydrocarbazoles, the main direction of the process was complete aromatization of the polycyclic system. Besides the influence of the substrate type, we also explored the role of various oxidants, solvents, and the concentration of reactants in this oxidation process.

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Authors and Affiliations

  1. Belarusian State Technological University, 13a Sverdlova St, 220006, Minsk, Belarus

    Sergei G. Mikhalyonok, Alexander I. Savelyev, Nina M. Kuz’menok & Vladimir S. Bezborodov

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  1. Sergei G. Mikhalyonok
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  2. Alexander I. Savelyev
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  3. Nina M. Kuz’menok
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  4. Vladimir S. Bezborodov
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Correspondence to Alexander I. Savelyev.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2022, 58(8/9), 403–411

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Mikhalyonok, S.G., Savelyev, A.I., Kuz’menok, N.M. et al. Chemo- and regioselective oxidation of substituted 2,3,4,9-tetrahydro-1H-carbazoles. Chem Heterocycl Comp 58, 403–411 (2022). https://doi.org/10.1007/s10593-022-03106-6

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