This microreview focuses on the main modern synthetic approaches toward polyhydroquinolines, which represent a significant group of N-heterocycles of great interest due to the wide range of their pharmacological activities. In the last five years, several strategies with heterogeneous nanostructured catalytic systems have been adapted to the Hantzsch reaction to improve the yields of polyhydroquinolines and reduce the chemical impact on the environment. Thus, we consider it necessary to compile a systematic review of the most recent data (2017–2021).
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Kalaria, P. N.; Satasia, S. P.; Raval, D. K. Eur. J. Med. Chem. 2014, 78, 207.
(a) Kumar, A.; Sharma, S.; Tripathi, V. D.; Maurya, R. A.; Srivastava, S. P.; Bhatia, G.; Tamrakar, A. K.; Srivastava, A. K. Bioorg. Med. Chem. 2010, 18, 4138. (b) Rose, U., Draeger, M. J. Med. Chem. 1992, 35, 2238. (c) Yang, X. H.; Xiao, G. M.; Wang, Z. M.; Zhou, Y. H.; Feng, G. D. Adv. Mater. Res. 2012, 581–582, 7. (d) Jadhvar, S. C.; Kasraliker, H. M.; Goswami, S. V.; Chakrawar, A. V.; Bhusare, S. R. Res. Chem. Intermed. 2017, 43, 7211. (e) Brinkerhoff, R. C.; Santa-Helena, E.; do Amaral, P. C.; Cabrera, D. da C.; Ongaratto, R. F.; de Oliveira, P. M.; D'Oca, C. Da R. M.; Goncalves, C. A. N.; Nery, L. E. M.; D'Oca, M. G. M. RSC Adv. 2019, 9, 24688.
Kumar, A.; Maurya, R. A. Tetrahedron 2007, 63, 1946.
Li, M.; Guan, J. Adv. Org. Synth. 2017, 7, 228.
Anantha, I. S. S.; Kerru, N.; Maddila, S.; Jonnalagadda, S. B. Front. Chem. 2021, 9, 800236.
Mathur, R.; Negi, K. S.; Shrivastava, R.; Nair, R. RSC Adv. 2021, 11, 1376.
Kazemi, M.; Mohammadi, M. Appl. Organomet. Chem. 2020, 34, e5400.
Hashemi-Uderji, S.; Abdollahi-Alibeik, M.; Ranjbar-Karimi, R. Main Group Met. Chem. 2018, 41, 91.
Shaker, M.; Beni, A. S. J. Porous Mater. 2021, 28, 435.
Bazdid-Vahdaty, N.; Mamaghani, M.; Khalili, B.; Tavakoli, F. J. Chil. Chem. Soc. 2021, 66, 5136.
Elhamifar, D.; Khanmohammadi, H.; Elhamifar, D. RSC Adv. 2017, 7, 54789.
Ramish, S. M.; Ghorbani-Choghamarani, A.; Mohammadi, M. Res. Square 2021. https://doi.org/10.21203/rs.3.rs-955041/v1
Rostamnia, S.; Alamgholiloo, H.; Jafari, M. Appl. Organomet. Chem. 2018, 32, e4370.
Hussain-Khil, N.; Ghorbani-Choghamarani, A.; Mohammadi, M. Sci. Rep. 2021, 11, Article No. 15657.
Zare, E.; Rafiee, Z. J. Taiwan Inst. Chem. Eng. 2020, 116, 205.
Maleki, A.; Eskandarpour, V.; Rahimi, J.; Hamidi, N. Carbohydr. Polym. 2019, 208, 251.
Asgharnasl, S.; Eivazzadeh-Keihan, R.; Radinekiyan, F.; Maleki, A. Int. J. Biol. Macromol. 2020, 144, 29.
Nosrati, A.; Amirnejat, S.; Javanshir, S. ChemistryOpen 2021, 10, 1186.
Rakhtshah, J.; Salehzadeh, S.; Zolfigol, M. A.; Baghery, S. J. Coord. Chem. 2017, 70, 340.
Moradi, L.; Zare, M. Green Chem. Lett. Rev. 2018, 11, 197.
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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2022, 58(8/9), 397–399
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Leyva-Acuña, M.A., Montes-Avila, J. 
Heterogeneous nanostructured catalysts in the synthesis of polyhydroquinolines (microreview).
Chem Heterocycl Comp 58, 397–399 (2022). https://doi.org/10.1007/s10593-022-03104-8
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DOI: https://doi.org/10.1007/s10593-022-03104-8