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Cyclocondensation of 5-chloro-4-formylpyrrole-3-carboxylates with arylamines. Synthesis and fluorescent properties of pyrrolo[2,3-b]quinoline-3-carboxylates and their benzo[f] analogs

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Chemistry of Heterocyclic Compounds Aims and scope

5-Chloro-4-formylpyrrole-3-carboxylates react with anilines or β-naphthylamine when heated in DMF under reflux to form ethyl pyrrolo[2,3-b]quinoline-3-carboxylates or their benzo[f] analogs, which exhibit moderate fluorescent properties. The corresponding carboxylic acids were obtained by alkaline hydrolysis of the synthesized carboxylates.

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Authors and Affiliations

  1. Bukovinian State Medical University, 2 Teatral’na Sq, Chernivtsi, 58000, Ukraine

    Alina N. Grozav & Vitaliy А. Chornous

  2. Ivano-Frankivsk National Medical University, 2 Galytska St, Ivano-Frankivsk, 76018, Ukraine

    Mariana Z. Fedoriv

  3. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St, Kyiv, 02094, Ukraine

    Sergiy V. Kemskiy, Vladislav M. Polishchuk, Nikolay P. Shandura, Eduard B. Rusanov & Mikhailo V. Vovk

Authors
  1. Alina N. Grozav
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  2. Mariana Z. Fedoriv
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  3. Vitaliy А. Chornous
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  4. Sergiy V. Kemskiy
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  5. Vladislav M. Polishchuk
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  6. Nikolay P. Shandura
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  7. Eduard B. Rusanov
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  8. Mikhailo V. Vovk
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Correspondence to Alina N. Grozav.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2021, 57(10), 1024–1030

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Grozav, A.N., Fedoriv, M.Z., Chornous, V.А. et al. Cyclocondensation of 5-chloro-4-formylpyrrole-3-carboxylates with arylamines. Synthesis and fluorescent properties of pyrrolo[2,3-b]quinoline-3-carboxylates and their benzo[f] analogs. Chem Heterocycl Comp 57, 1024–1030 (2021). https://doi.org/10.1007/s10593-021-03017-y

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  • DOI: https://doi.org/10.1007/s10593-021-03017-y

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