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Priority directions in the design of biologically active compounds based on 2-aminopyrimidin-4(3H)-one and its derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

This review compiles literature data on the design of biologically active compounds based on 2-aminopyrimidin-4(3H)-one and its derivatives over the past 20 years. The systematization and analysis of the collected data made it possible to identify the priority directions of this process, including the development of antiviral and antileukemic agents, drugs for combating hyperuricemia, neurodegenerative disorders, some forms of cancer and, finally, anti-inflammatory and hormonal drugs.

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  1. Saint Petersburg State Institute of Technology (Technical University), 26 Moskovsky Ave, Saint Petersburg, 190013, Russia

    Andrei V. Erkin, Viktor I. Krutikov & Alexander V. Garabadzhiu

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  1. Andrei V. Erkin
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  2. Viktor I. Krutikov
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2021, 57(2), 103–121

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Erkin, A.V., Krutikov, V.I. & Garabadzhiu, A.V. Priority directions in the design of biologically active compounds based on 2-aminopyrimidin-4(3H)-one and its derivatives. Chem Heterocycl Comp 57, 103–121 (2021). https://doi.org/10.1007/s10593-021-02875-w

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