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Fluorinated tetraketone derivatives of N-substituted carbazoles and their Eu(III) complexes for fluorescence immunoassay

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Chemistry of Heterocyclic Compounds Aims and scope

New fluorinated tetraketone derivatives of N-substituted carbazoles were synthesized and tested as ligands for fluorescence immunoassay. The spectral properties of the obtained heterocyclic tetraketones and their Eu(III) complexes were studied. The complexes showed longwave absorption at 360–380 nm, high extinction coefficient values, long lifetime of excited states, and intense luminescence, allowing to consider the use of such lanthanide complexes in immunofluorescence analysis.

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Authors and Affiliations

  1. Moscow State Regional University, 10а Radio St., Moscow, 105005, Russia

    Dmitriy E. Pugachov & Nikolai V. Vasil’ev

  2. State Research Institute of Biological Engineering, 75/1 Volokolamskoe Shosse, Moscow, 125424, Russia

    Dmitriy E. Pugachov, Tatiana S. Kostryukova, Georgy V. Zatonsky & Nikolai V. Vasil’ev

  3. Lomonosov Moscow State University, 1-3 Leninskie Gory, Moscow, 119991, Russia

    Sergey Z. Vatsadze

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  1. Dmitriy E. Pugachov
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  2. Tatiana S. Kostryukova
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  3. Georgy V. Zatonsky
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  4. Sergey Z. Vatsadze
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  5. Nikolai V. Vasil’ev
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Correspondence to Nikolai V. Vasil’ev.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2018, 54(5), 528–534

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Pugachov, D.E., Kostryukova, T.S., Zatonsky, G.V. et al. Fluorinated tetraketone derivatives of N-substituted carbazoles and their Eu(III) complexes for fluorescence immunoassay. Chem Heterocycl Comp 54, 528–534 (2018). https://doi.org/10.1007/s10593-018-2300-4

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  • DOI: https://doi.org/10.1007/s10593-018-2300-4

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