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Synthesis of 4-(4-oxo-1,3-thiazolidin-2-ylidene)-pyrrolidine-2,3,5-triones

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Chemistry of Heterocyclic Compounds Aims and scope

It was shown that 2-(1,3-thiazolidin-2-ylidene)acetamides can be used as 2-enamides in cyclocondensation reactions with oxalyl chloride, leading to the formation of new heterocyclic assemblies – 4-(4-oxo-1,3-thiazolidin-2-ylidene)pyrrolidine-2,3,5-triones in 50–88% yields.

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This work was performed with financial support from the Russian Foundation for Basic Research (grant 16-33-00560 mol_a) and the Government of Russian Federation (assignment No. 211, contract No. 02.A03.21.0006).

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Authors and Affiliations

  1. Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mir St., Yekaterinburg, 620002, Russia

    Konstantin L. Obydennov, Aleksei N. Galushchinskiy, Marya F. Kosterina, Tatiana V. Glukhareva & Yuri Yu. Morzherin

Authors
  1. Konstantin L. Obydennov
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  2. Aleksei N. Galushchinskiy
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  3. Marya F. Kosterina
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  4. Tatiana V. Glukhareva
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  5. Yuri Yu. Morzherin
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Corresponding author

Correspondence to Konstantin L. Obydennov.

Additional information

Supplementary information file containing IR, 1Н and 13С NMR, and mass spectra of compounds 1a–e, 3a–e, is available from the journal website at http://link.springer.com/journal/10593.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2017, 53(5), 622–625

Yuri Yu. Morzherin is deceased.

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Obydennov, K.L., Galushchinskiy, A.N., Kosterina, M.F. et al. Synthesis of 4-(4-oxo-1,3-thiazolidin-2-ylidene)-pyrrolidine-2,3,5-triones. Chem Heterocycl Comp 53, 622–625 (2017). https://doi.org/10.1007/s10593-017-2102-0

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