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Reduction of 5-(indol-3-yl)pyrrolidin-2-ones

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Chemistry of Heterocyclic Compounds Aims and scope

The reduction of activated 5-(indol-3-yl)pyrrolidin-2-ones leading to a mixture of the respective indolyl pyrrolidines and their borane complexes, as well as several other transformations indicate that the electrophilicity of carbonyl group in 5-indolylpyrrolidin-2-ones is significantly decreased.

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Notes

  1. Here and below М(base) – the molar mass of the base.

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Authors and Affiliations

  1. M. V. Lomonosov Moscow State University, 1, Build. 3 Leninskie Gory, Moscow, 119991, Russia

    Andrey V. Sadovoy, Vita N. Nikitina, Victor B. Rybakov & Lyudmila A. Sviridova

  2. A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilova St., Moscow, 119991, Russia

    Konstantin A. Kochetkov

Authors
  1. Andrey V. Sadovoy
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  2. Vita N. Nikitina
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  3. Victor B. Rybakov
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  4. Konstantin A. Kochetkov
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  5. Lyudmila A. Sviridova
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Corresponding author

Correspondence to Lyudmila A. Sviridova.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2016, 52(1), 21–24

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Sadovoy, A.V., Nikitina, V.N., Rybakov, V.B. et al. Reduction of 5-(indol-3-yl)pyrrolidin-2-ones. Chem Heterocycl Comp 52, 21–24 (2016). https://doi.org/10.1007/s10593-016-1832-8

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  • DOI: https://doi.org/10.1007/s10593-016-1832-8

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