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Synthesis of 2-amino-6-oxo-5-salicyloyl-1,6-dihydropyridine- 3-carboxamides from 3-carbamoylchromones and cyanoacetamides

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Chemistry of Heterocyclic Compounds Aims and scope

3-Carbamoylchromones reacted with cyanoacetamides in the presence of sodium ethoxide in refluxing ethanol, forming 2-amino-5-aroyl- 6-oxo-1,6-dihydropyridine-3-carboxamides in 50–88% yields.

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The work was performed with financial support from the Russian Science Fund (Project No. 14-13-00388).

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Authors and Affiliations

  1. Institute of Natural Sciences, Ural Federal University named after the First President of Russia B. N. Yeltsin, 51 Lenina Ave, Yekaterinburg, 620000, Russia

    Mikhail Yu. Kornev, Vladimir S. Moshkin & Vyacheslav Ya. Sosnovskikh

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  1. Mikhail Yu. Kornev
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  2. Vladimir S. Moshkin
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  3. Vyacheslav Ya. Sosnovskikh
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Correspondence to Vyacheslav Ya. Sosnovskikh.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2015, 51(7), 688–690

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Kornev, M.Y., Moshkin, V.S. & Sosnovskikh, V.Y. Synthesis of 2-amino-6-oxo-5-salicyloyl-1,6-dihydropyridine- 3-carboxamides from 3-carbamoylchromones and cyanoacetamides. Chem Heterocycl Comp 51, 688–690 (2015). https://doi.org/10.1007/s10593-015-1758-6

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  • DOI: https://doi.org/10.1007/s10593-015-1758-6

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