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Synthesis and Aminomethylation of 3-Substituted 6-Hydroxy-1,2-Benzisoxazoles

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Chemistry of Heterocyclic Compounds Aims and scope

Oximes of 2,4-dihydroxybenzophenones, 1-(2,4-dihydroxyphenyl)-2-phenylethanones, and 1-(2,4-di-hydroxyphenyl)-2-phenoxyethanones were dehydrated with 1,1'-carbonyldiimidazole, yielding 3-substi-tuted 6-hydroxy-1,2-benzisoxazoles, aminomethylation reactions of which were studied with various reagents.

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Authors and Affiliations

  1. Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, 1 Murmanska St., Kyiv, 02094, Ukraine

    M. S. Frasinyuk

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  1. M. S. Frasinyuk
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Correspondence to M. S. Frasinyuk.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1758-1765, November, 2014.

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Frasinyuk, M.S. Synthesis and Aminomethylation of 3-Substituted 6-Hydroxy-1,2-Benzisoxazoles. Chem Heterocycl Comp 50, 1616–1623 (2015). https://doi.org/10.1007/s10593-014-1631-z

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  • DOI: https://doi.org/10.1007/s10593-014-1631-z

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