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Synthesis of bis-heterocyclic compounds with a phenylene bridge from 1,4- and 1,3-bis(2-chloro-2-cyanovinyl)benzenes

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Chemistry of Heterocyclic Compounds Aims and scope

Reaction of binucleophiles with 1,4- and 1,3-bis(2-chloro-2-cyanovinyl)benzenes, synthesized using a catalytic olefination of terephthalic and isophthalic aldehydes, gave high yields of aminopyrazoles, 3-amino-5-arylthiophene-2-carboxylic acid esters, and 2,4-diamino-6-arylpyrimidines.

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Authors and Affiliations

  1. Lomonosov Moscow State University, 1 Leninskie Gory, Moscow, 119991, Russia

    V. M. Muzalevskiy, E. S. Balenkova & V. G. Nenajdenko

  2. Baku State University, 23 Acad. Z. Khalilov St., Baku, AZ1148, Azerbaijan

    A. M. Maharramov, N. G. Shikhaliev, S. Dzh. Geidarova & M. A. Mamedova

  3. Institute of Problems of Chemical Physics, Russian Academy of Sciences, 1 Acad. Semenov Ave., Chernogolovka, 142432, Russia

    A. V. Shastin

Authors
  1. V. M. Muzalevskiy
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  2. A. M. Maharramov
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  3. N. G. Shikhaliev
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  4. S. Dzh. Geidarova
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  6. E. S. Balenkova
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  7. A. V. Shastin
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  8. V. G. Nenajdenko
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Correspondence to V. G. Nenajdenko.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 973-979, June, 2013.

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Muzalevskiy, V.M., Maharramov, A.M., Shikhaliev, N.G. et al. Synthesis of bis-heterocyclic compounds with a phenylene bridge from 1,4- and 1,3-bis(2-chloro-2-cyanovinyl)benzenes. Chem Heterocycl Comp 49, 909–914 (2013). https://doi.org/10.1007/s10593-013-1325-y

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  • DOI: https://doi.org/10.1007/s10593-013-1325-y

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