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Studies of benzoxazines 16*. Synthesis and reactivity of 2,4-substituted 4H-3,1-benzoxazines

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Chemistry of Heterocyclic Compounds Aims and scope

A novel method has been developed for preparation of substituted 4H-3,1-benzoxazines via formation of tetrafluoroborates. The substitution of halogen in 2-(α-haloalkyl)-4,4-diphenyl-4H-3,1-benzoxazines by NH and SH nucleophiles was performed. The effect of electrophilic substitution in the annelated aromatic ring in a series of 2,4-substituted 4H-3,1-benzoxazines has been studied.

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Authors and Affiliations

  1. Research Institute of Heterocyclic Compounds Chemistry, Kuban State Technological University, 2 Moscovskaya St., Krasnodar, 350072, Russia

    E. V. Gromachevskaya, V. G. Kul’nevich & T. P. Kosulina

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  1. E. V. Gromachevskaya
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  2. V. G. Kul’nevich
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  3. T. P. Kosulina
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Correspondence to E. V. Gromachevskaya.

Additional information

For Communication 15, see [1].

Deceased.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1691-1701, November, 2011.

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Gromachevskaya, E.V., Kul’nevich, V.G. & Kosulina, T.P. Studies of benzoxazines 16*. Synthesis and reactivity of 2,4-substituted 4H-3,1-benzoxazines. Chem Heterocycl Comp 47, 1405–1414 (2012). https://doi.org/10.1007/s10593-012-0928-z

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  • DOI: https://doi.org/10.1007/s10593-012-0928-z

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