Syntheses were developed for 4-aryl-6-ethoxy-2-R-furo[2,3-b]pyridine-5-carbonitriles and ethyl esters of 5-amino-4-aryl-7-methyl-2-R-1,9-dioxa-8-azacyclopenta[b]naphthalene-6-carboxylic acids based on the reaction of 6-amino-4-aryl-2-R-4H-furo[2,3-b]pyran-5-carbonitriles with ethyl acetoacetate and nucleophilic recyclization. The mechanisms of these reactions are considered.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1812-1816, December, 2009.
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Anis’kova, T.V., Chadina, V.V. & Yegorova, A.Y. Synthesis of polyheterocyclic compounds derived from 6-amino- 4-aryl-2-r-4h-furo[2,3-b]pyran-5-carbonitriles. Chem Heterocycl Comp 45, 1460–1463 (2009). https://doi.org/10.1007/s10593-010-0450-0
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DOI: https://doi.org/10.1007/s10593-010-0450-0