Alkylation of 3-methoxycarbonyl-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine and 12-oxo-12,13-dihydro-7H-7azaindeno[1,2-b]phenanthrene using methyl iodide or allyl bromide in DMF solution in the presence of NaH occurs with high selectivity and gives the corresponding C-alkyl derivatives in high yield. The acid cleavage of the 4a-alkylated 3-methoxycarbonyl-2-methyl-5-oxo-4a,5-dihydroindeno[1,2-b]pyridines has been studied.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 415–420, March, 2009.
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Tanaev, D., Lusis, V. & Muceniece, D. Reactions of 4-unsubstituted 4,5-dihydro-1H-indeno[1,2-b]pyridines. Chem Heterocycl Comp 45, 336–340 (2009). https://doi.org/10.1007/s10593-009-0270-2
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DOI: https://doi.org/10.1007/s10593-009-0270-2