A simple and efficient method for preparing 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid alkyl amides is proposed. The results of a study of the diuretic activity of the compounds synthesized are reported.
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I. V. Ukrainets, A. A. Tkach, and Liu Yang Yang, Khim. Geterotsikl. Soedin., 1655 (2008). [Chem. Heterocycl. Comp., 44, 1347 (2008)].
I. V. Ukrainets, O. V. Gorokhova, and L. V. Sidorenko, Khim. Geterotsikl. Soedin., 1195 (2005). [Chem. Heterocycl. Comp., 41, 1019 (2005)].
I. V. Ukrainets, N. L. Bereznyakova, V. A. Parshikov, and V. N. Kravchenko, Khim. Geterotsikl. Soedin., 78 (2008). [Chem. Heterocycl. Comp., 44, 64 (2008)].
I. V. Ukrainets, N. L. Bereznyakova, V. A. Parshikov, and O. I. Naboka, Khim. Geterotsikl. Soedin., 239 (2008). [Chem. Heterocycl. Comp., 44, 178 (2008)].
L. F. Fieser and M. Fieser, Reagents for Organic Synthesis [Russian translation], Vol. 2, Mir, Moscow (1970), p. 120.
Y. V. Zefirov, Kristallografiya, 42, 936 (1997).
H. -B. Burgi and J. D. Dunitz, Structural Correlation, Vol. 2, VCH, Weinheim (1994), p. 741.
I. V. Ukrainets, N. L. Bereznyakova, and E. V. Mospanova, Khim. Geterotsikl. Soedin., 1015 (2007). [Chem. Heterocycl. Comp., 43, 856 (2007)].
L. N. Sernov and V. V. Gatsura, Elements of Experimental Pharmacology [in Russian], Moscow (2000), p. 103.
G. M. Sheldrick, SHELXTL PLUS. PC Version. A System of Computer Programs for the Determination of Crystal Structure from X-ray Diffraction Data, Rev. 5.1 (1998).
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*For communication 149 see [1].
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1841-1848, December, 2008.
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Ukrainets, I.V., Bereznyakova, N.L., Parshikov, V.A. et al. 4-Hydroxy-2-quinolones 150*. Efficient synthesis, structure, and biological activities of 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid alkyl amides. Chem Heterocycl Comp 44, 1493–1499 (2008). https://doi.org/10.1007/s10593-009-0209-7
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DOI: https://doi.org/10.1007/s10593-009-0209-7