Skip to main content
SpringerLink
Log in

Study of nitrogen- and sulfur-containing heterocycles. 54. Properties and conversions of pyrimido[4,5-b]-1,4-benzothiazepines. Synthesis of a novel heterocyclic system: Pyrimido[5,4-c]isoquinoline

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

We have studied some properties and conversions of pyrimido[4,5-b]-1,4-benzothiazepines: reduction, oxidation, reactions with nucleophilic reagents (methanol, hydrazine, hydroxylamine, o-methylhydroxylamine, and thiosemicarbazide). We have synthesized derivatives of a novel heterocyclic system: pyrimido[5,4-c]isoquinoline.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. T. S. Safonova, M. P. Nemeryuk, N. A. Grineva, M. A. Keremov, and M. M. Likhovidova, Khim. Geterotsikl. Soedin., 270 (2001).

  2. T. S. Safonova, in: Targeted Discovery of New Anticancer and Antiviral Drugs [in Russian], Zinatne, Riga (1978), p. 51.

    Google Scholar 

  3. A. M. Polezhaeva, L. F. Roshchina, A. S. Sokolova, M. P. Nemeryuk, M. V. Pykhova, T. S. Safonova, and M. D. Mashkovskii, Khim.-Farm. Zh., 15, No.11, 45 (1981).

    Google Scholar 

  4. D. Beke, in: Advances in Heterocyclic Chemistry (A. R. Katritzky, ed.), Academic Press, New York/London (1963), Vol. 6, p. 167.

    Google Scholar 

  5. T. Koyama, T. Hirota, I. Shinohara, S. Fukuoka, M. Yamato, and S. Ohmori, Chem. Pharm. Bull., 23, 494 (1975).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Center for Drug Chemistry/All-Russian Scientific Research Pharmaceutical Chemistry Institute, 119815, Moscow

    T. S. Safonova, M. P. Nemeryuk, N. A. Grineva, O. S. Anisimova & N. P. Solov’eva

  2. Dagestan State University, 367010, Makhachkala, Russia

    A. F. Keremov

Authors
  1. T. S. Safonova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. P. Nemeryuk
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. A. Grineva
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. F. Keremov
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. O. S. Anisimova
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. N. P. Solov’eva
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1863–1872, December, 2004.

For Communication 53, see [1].

Rights and permissions

Reprints and permissions

About this article

Cite this article

Safonova, T.S., Nemeryuk, M.P., Grineva, N.A. et al. Study of nitrogen- and sulfur-containing heterocycles. 54. Properties and conversions of pyrimido[4,5-b]-1,4-benzothiazepines. Synthesis of a novel heterocyclic system: Pyrimido[5,4-c]isoquinoline. Chem Heterocycl Compd 40, 1609–1617 (2004). https://doi.org/10.1007/s10593-005-0105-8

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10593-005-0105-8

Keywords

Search

Navigation