Acevedo-Whitehouse K, Cunningham AA (2006) Is MHC enough for understanding wildlife immunogenetics? Trends Ecol Evol 21:433–438
PubMed
Article
Google Scholar
Aguilar A, Roemer G, Debenham S et al (2004) High MHC diversity maintained by balancing selection in an otherwise genetically monomorphic mammal. Proc Natl Acad Sci U S A 101:3490–3494
CAS
PubMed
PubMed Central
Article
Google Scholar
Alcaide M (2010) On the relative roles of selection and genetic drift in shaping MHC variation. Mol Ecol 19:3842–3844
PubMed
Article
Google Scholar
Anisimova M, Nielsen R, Yang Z (2003) Effect of recombination on the accuracy of the likelihood method for detecting positive selection at amino acid sites. Genetics 164:1229–1236
CAS
PubMed
PubMed Central
Google Scholar
Ardia DR, Parmentier HK, Vogel LA (2011) The role of constraints and limitation in driving individual variation in immune response. Funct Ecol 25:61–73
Article
Google Scholar
Barrett ELB, Burke TA, Hammers M et al (2013) Telomere length and dynamics predict mortality in a wild longitudinal study. Mol Ecol 22:249–259
PubMed
Article
Google Scholar
Basu M, Das T, Ghosh A et al (2012) Gene-gene interaction and functional impact of polymorphisms on innate immune genes in controlling Plasmodium falciparum blood infection level. PLoS One 7:e46441
CAS
PubMed
PubMed Central
Article
Google Scholar
Bensch S, Hasselquist D (1999) Phylogeographic population structure of great reed warblers: an analysis of mtDNA control region sequences. Biol J Linn Soc 66:171–185
Article
Google Scholar
Bollmer JL, Ruder EA, Johnson JA et al (2011) Drift and selection influence geographic variation at immune loci of prairie-chickens. Mol Ecol 20:4695–4706
PubMed
Article
Google Scholar
Brooke M (2010) Henderson Island. Br Birds 103:428–444
Google Scholar
Brooke MDL, Hartley IR (1995) Nesting Henderson reed-warblers (Acrocephalus vaughani taiti) studied by DNA fingerprinting : unrelated coalitions in a stable habitat? Auk 112:77–86
Article
Google Scholar
Brouwer L, Tinbergen JM, Both C et al (2009) Experimental evidence for density-dependent reproduction in a cooperatively breeding passerine. Ecology 90:729–741
PubMed
Article
Google Scholar
Brouwer L, Barr I, van de Pol M et al (2010) MHC-dependent survival in a wild population: evidence for hidden genetic benefits gained through extra-pair fertilizations. Mol Ecol 19:3444–3455
PubMed
Article
Google Scholar
Chow BT, Soto M, Lo BL et al (2012) Antibacterial activity of four human beta-defensins: HBD-19, HBD-23, HBD-27, and HBD-29. Polymers (Basel) 4:747–758
Article
Google Scholar
Collar NJ, Stuart SN (1985) Threatened birds of Africa and related islands. International Council for Bird Preservation, Cambridge
Delport W, Poon AFY, Frost SDW, Kosakovsky Pond SL (2010) Datamonkey 2010: a suite of phylogenetic analysis tools for evolutionary biology. Bioinformatics 26:2455–2457
CAS
PubMed
PubMed Central
Article
Google Scholar
Doherty PC, Zinkernagel RM (1975) Enhanced immunological surveillance in mice heterozygous at the H-2 gene complex. Nature 256:50–52
CAS
PubMed
Article
Google Scholar
Eimes JA, Bollmer JL, Whittingham LA et al (2011) Rapid loss of MHC class II variation in a bottlenecked population is explained by drift and loss of copy number variation. J Evol Biol 24:1847–1856
CAS
PubMed
Article
Google Scholar
Ellegren H, Sheldon BC (2008) Genetic basis of fitness differences in natural populations. Nature 452:169–175
CAS
PubMed
Article
Google Scholar
Felsenstein J (1985) Confidence limits on phylogenies: an approach using the bootstrap. Evolution 39:783–791
Article
Google Scholar
Ferrer-admetlla A, Bosch E, Sikora M et al (2008) Balancing selection is the main force shaping the evolution of innate immunity. J Immunol 181:1315–1322
CAS
PubMed
Article
Google Scholar
Fitzpatrick MJ, Ben-Shahar Y, Smid HM et al (2005) Candidate genes for behavioural ecology. Trends Ecol Evol 20:96–104
PubMed
Article
Google Scholar
Frankel OH (1974) Genetic conservation: our evolutionary responsibility. Genetics 78:53–65
CAS
PubMed
PubMed Central
Google Scholar
Frankham R (1995) Conservation genetics. Annu Rev Genet 29:305–327
CAS
PubMed
Article
Google Scholar
Fu Y-X (1996) New statistical tests of neutrality for DNA samples from a population. Genetics 143:557–570
CAS
PubMed
PubMed Central
Google Scholar
Fu Y-X, Li W-H (1993) Statistical tests of neutrality of mutations. Genetics 133:693–709
CAS
PubMed
PubMed Central
Google Scholar
Garrigan D, Hedrick PW (2003) Perspective: detecting adaptive molecular polymorphism: lessons from the MHC. Evolution 57:1707–1722
CAS
PubMed
Article
Google Scholar
Grueber CE, Carolyn J (2015) Impacts of early viability selection on management of inbreeding and genetic diversity in conservation. Mol Ecol 24:1645–1653
PubMed
Article
Google Scholar
Grueber CE, Wallis GP, Jamieson IG (2013) Genetic drift outweighs natural selection at toll-like receptor (TLR) immunity loci in a re-introduced population of a threatened species. Mol Ecol 22:4470–4482
CAS
PubMed
Article
Google Scholar
Hagemeijer WJM, Blair MJ (1997) The EBCC Atlas of European Breeding Birds. T & AD Poyser, London
Hall TA (1999) BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucleic Acids Symp 41:95–98
CAS
Google Scholar
Hancock REW, Sahl H-G (2006) Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat Biotechnol 24:1551–1557
CAS
PubMed
Article
Google Scholar
Hansson B, Richardson DS (2005) Genetic variation in two endangered Acrocephalus species compared to a widespread congener: estimates based on functional and random loci. Anim Conserv 8:83–90
Article
Google Scholar
Hansson B, Jack L, Christians JK et al (2006) No evidence for inbreeding avoidance in a great reed warbler population. Behav Ecol 18:157–164
Article
Google Scholar
Hedrick PW (2001) Conservation genetics: where are we now? Trends Ecol Evol 16:629–636
Article
Google Scholar
Hedrick PW, Gutierrez-Espeleta GA, Lee RN (2001) Founder effect in an island population of bighorn sheep. Mol Ecol 10:851–857
CAS
PubMed
Article
Google Scholar
Hellgren O (2015) Allelic variation at innate immune genes (avian β-defensins), within a natural population of great tits. J Avian Biol 46:113–118
Article
Google Scholar
Hellgren O, Ekblom R (2010) Evolution of a cluster of innate immune genes (beta-defensins) along the ancestral lines of chicken and zebra finch. Immunome Res 6:3
PubMed
PubMed Central
Article
CAS
Google Scholar
Hellgren O, Sheldon BC (2011) Locus-specific protocol for nine different innate immune genes (antimicrobial peptides: beta-defensins) across passerine bird species reveals within-species coding variation and a case of trans-species polymorphisms. Mol Ecol Resour 11:686–692
CAS
PubMed
Article
Google Scholar
Hellgren O, Sheldon BC, Buckling A (2010) In vitro tests of natural allelic variation of innate immune genes (avian β-defensins) reveal functional differences in microbial inhibition. J Evol Biol 23:2726–2730
CAS
PubMed
Article
Google Scholar
Higgs R, Lynn DJ, Cahalane S et al (2007) Modification of chicken avian beta-defensin-8 at positively selected amino acid sites enhances specific antimicrobial activity. Immunogenetics 59:573–580
CAS
PubMed
Article
Google Scholar
Hogg JT, Forbes SH, Steele BM, Luikart G (2006) Genetic rescue of an insular population of large mammals. Proc Biol Sci 273:1491–1499
PubMed
PubMed Central
Article
Google Scholar
Hollox EJ, Armour JA (2008) Directional and balancing selection in human beta-defensins. BMC Evol Biol 8:113
PubMed
PubMed Central
Article
CAS
Google Scholar
Hutchings K (2009) Parasite-mediated selection in an island endemic, the Seychelles warbler (Acrocephalus sechellensis). University of East Anglia
IUCN (2015) The IUCN Red List of Threatened Species. Version 2015-4. http://www.iucnredlist.org
Jamieson IG (2011) Founder effects, inbreeding, and loss of genetic diversity in four avian reintroduction programs. Conserv Biol 25:115–123
PubMed
Article
Google Scholar
Jeffery KJM, Bangham CRM (2000) Do infectious diseases drive MHC diversity? Microbes Infect 2:1335–1341
CAS
PubMed
Article
Google Scholar
Jensen H, Moe R, Hagen IJ et al (2013) Genetic variation and structure of house sparrow populations: is there an island effect? Mol Ecol 22:1792–1805
PubMed
Article
Google Scholar
Jukes TH, Cantor CR (1969) Evolution of protein molecules. In: Munro HN (ed) Mammalian protein metabolism. Academic Press, New York
Google Scholar
Kaiser P (2007) The avian immune genome–a glass half-full or half-empty? Cytogenet Genome Res 117:221–230
CAS
PubMed
Article
Google Scholar
Kimura M (1980) A simple method for estimating evolutionary rate of base substitutions through comparative studies of nucleotide sequences. J Mol Evol 16:111–120
CAS
PubMed
Article
Google Scholar
Klein J (1986) Natural history of the major histocompatibility complex. Wiley, New York
Google Scholar
Knowles SC, Wood MJ, Alves R et al (2011) Molecular epidemiology of malaria prevalence and parasitaemia in a wild bird population. Mol Ecol 20:1062–1076
PubMed
Article
Google Scholar
Komdeur J (1992) Importance of habitat saturation and territory quality for evolution of cooperative breeding in the Seychelles warbler. Nature 358:493–495
Article
Google Scholar
Komdeur J (1994) Conserving the Seychelles warbler Acrocephalus sechellensis by translocation from Cousin island to the islands of Aride and Cousine. Biol Conserv 67:143–152
Article
Google Scholar
Lazzaro BP (2008) Natural selection on the Drosophila antimicrobial immune system. Curr Opin Microbiol 11:284–289
CAS
PubMed
PubMed Central
Article
Google Scholar
Librado P, Rozas J (2009) DnaSP v5: a software for comprehensive analysis of DNA polymorphism data. Bioinformatics 25:1451–1452
CAS
PubMed
Article
Google Scholar
Lynn DJ, Higgs R, Gaines S et al (2004) Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken. Immunogenetics 56:170–177
CAS
PubMed
Article
Google Scholar
Ma D, Zhou C, Zhang M et al (2012) Functional analysis and induction of four novel goose (Anser cygnoides) avian beta-defensins in response to salmonella enteritidis infection. Comp Immunol Microbiol Infect Dis 35:197–207
PubMed
Article
Google Scholar
Marchini J, Cutler D, Patterson N et al (2006) A comparison of phasing algorithms for trios and unrelated individuals. Am J Hum Genet 78:437–450
CAS
PubMed
PubMed Central
Article
Google Scholar
Meredith JM, Hurd H, Lehane MJ, Eggleston P (2008) The malaria vector mosquito Anopheles gambiae expresses a suite of larval-specific defensin genes. Insect Mol Biol 17:103–112
CAS
PubMed
PubMed Central
Article
Google Scholar
Meyers LA, Bull JJ (2002) Fighting change with change: adaptive variation in an uncertain world. Trends Ecol Evol 17:551–557
Article
Google Scholar
Miller HC, Lambert DM (2004) Genetic drift outweighs balancing selection in shaping post-bottleneck major histocompatibility complex variation in New Zealand robins (Petroicidae). Mol Ecol 13:3709–3721
CAS
PubMed
Article
Google Scholar
Mukherjee S, Sarkar-roy N, Wagener DK, Majumder PP (2009) Signatures of natural selection are not uniform across genes of innate immune system, but purifying. PNAS 106:7073–7078
PubMed
PubMed Central
Article
Google Scholar
Murrell B, Wertheim JO, Moola S et al (2012) Detecting individual sites subject to episodic diversifying selection. PLoS Genet 8:e1002764
CAS
PubMed
PubMed Central
Article
Google Scholar
Murrell B, Moola S, Mabona A et al (2013) FUBAR: a fast, unconstrained bayesian approximation for inferring selection. Mol Biol Evol Evol 30:1196–1205
CAS
Article
Google Scholar
Nei M (1987) Molecular evolutionary genetics. Columbia University Press, New York
Google Scholar
Nei M, Kumar S (2000) Molecular evolution and phylogenetics. Oxford University Press, New York
Google Scholar
O’Brien SJ, Evermann J (1988) FInteractive influence of infectious disease and genetic diversity in natural populations. Trends Ecol Evol 3:254–259
PubMed
Article
Google Scholar
Ohta T (1995) Gene conversion vs point mutation in generating variability at the antigen recognition site of major histocompatibility complex loci. J Mol Evol 41:115–119
CAS
PubMed
Google Scholar
Pertoldi C, Bijlsma R, Loeschcke V (2007) Conservation genetics in a globally changing environment: present problems, paradoxes and future challenges. Biodivers Conserv 16:4147–4163
Article
Google Scholar
Piertney SB, Oliver MK (2006) The evolutionary ecology of the major histocompatibility complex. Heredity 96:7–21
CAS
PubMed
Google Scholar
Pimm SL, Dollar L, Bass OL (2006) The genetic rescue of the Florida panther. Anim Conserv 9:115–122
Article
Google Scholar
Potts WK, Slev PR (1995) Pathogen-based models favoring MHC genetic diversity. Immunol Rev 143:181–197
CAS
PubMed
Article
Google Scholar
Radwan J, Zagalska-Neubauer M, Cichon M et al (2012) MHC diversity, malaria and lifetime reproductive success in collared flycatchers. Mol Ecol 21:2469–2479
PubMed
Article
Google Scholar
Ramasamy KT, Verma P, Reddy MR (2012) Differential gene expression of antimicrobial peptides beta defensins in the gastrointestinal tract of Salmonella serovar Pullorum infected broiler chickens. Vet Res Commun 36:57–62
PubMed
Article
Google Scholar
Raymond M, Rousset F (1995) GENEPOP (Version 1.2): population genetics software for exact tests and ecumenicism. Heredity 86:248–249
Google Scholar
Richardson DS, Westerdahl H (2003) MHC diversity in two Acrocephalus species: the outbred Great reed warbler and the inbred Seychelles warbler. Mol Evol 12:3523–3529
CAS
Google Scholar
Richardson DL, Jury FL, Dawson DA et al (2000) Fifty Seychelles warbler (Acrocephalus sechellensis) microsatellite loci polymorphic in Sylviidae species and their cross-species amplification in other passerine birds. Mol Ecol 9:2155–2157
Article
Google Scholar
Richardson DS, Jury FL, Blaakmeer K et al (2001) Parentage assignment and extra-group paternity in a cooperative breeder: the Seychelles warbler (Acrocephalus sechellensis). Mol Ecol 10:2263–2273
CAS
PubMed
Article
Google Scholar
Richardson DS, Burke T, Komdeur J (2002) Direct benefits and the evolution of female-biased cooperative breeding in Seychelles warblers. Evolution 56:2313–2321
PubMed
Article
Google Scholar
Richardson DS, Komdeur J, Burke T, Lusk C (2003) Altruism and infidelity among warblers. Nature 422:580–581
CAS
PubMed
Article
Google Scholar
Richardson DS, Komdeur J, Burke T, von Schantz T (2005) MHC-based patterns of social and extra-pair mate choice in the Seychelles warbler. Proc R Soc B 272:759–767
PubMed
PubMed Central
Article
Google Scholar
Richardson DS, Bristol R, Shah NJ (2006) Translocation of the Seychelles warbler Acrocephalus sechellensis to establish a new population on Denis Island, Seychelles. Conserv Evid 3:54–57
Google Scholar
Safford R, Hawkins F (2013) The birds of Africa, vol 8. The Malagasy Region, London
Google Scholar
Saitou N, Nei M (1987) The neighbour-joining method: a new method for reconstructing phylogentic trees. Mol Biol Evol 4:406–425
CAS
PubMed
Google Scholar
Schlenke TA, Begun DJ (2003) Natural selection drives Drosophila immune system evolution. Genetics 164:1471–1480
CAS
PubMed
PubMed Central
Google Scholar
Schulze-Hagen K, Leisler B (2011) Reed warblers: diversity in a uniform bird family, 1st edn. KNNV Uitgeverij, Zeist
Google Scholar
Selsted ME, Ouellette AJ (2005) Mammalian defensins in the antimicrobial immune response. Nat Immunol 6:551–557
CAS
PubMed
Article
Google Scholar
Sommer S (2005) The importance of immune gene variability (MHC) in evolutionary ecology and conservation. Front Zool 2:16
PubMed
PubMed Central
Article
CAS
Google Scholar
Spurgin LG, Richardson DS (2010) How pathogens drive genetic diversity: MHC, mechanisms and misunderstandings. Proc R Soc B 277:979–988
CAS
PubMed
PubMed Central
Article
Google Scholar
Spurgin LG, van Oosterhout C, Illera JC et al (2011) Gene conversion rapidly generates major histocompatibility complex diversity in recently founded bird populations. Mol Ecol 20:5213–5225
CAS
PubMed
Article
Google Scholar
Spurgin LG, Wright DJ, van der Velde M et al (2014) Museum DNA reveals the demographic history of the endangered Seychelles warbler. Evol Appl 7:1134–1143
PubMed
PubMed Central
Article
Google Scholar
Stephens M, Donnelly P (2003) A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet 73:1162–1169
CAS
PubMed
PubMed Central
Article
Google Scholar
Stephens M, Smith NJ, Donnelly P (2001) A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 68:978–989
CAS
PubMed
PubMed Central
Article
Google Scholar
Sugiarto H, Yu PL (2004) Avian antimicrobial peptides: the defense role of beta-defensins. Biochem Biophys Res Commun 323:721–727
CAS
PubMed
Article
Google Scholar
Sutton JT, Nakagawa S, Robertson BC, Jamieson IG (2011) Disentangling the roles of natural selection and genetic drift in shaping variation at MHC immunity genes. Mol Ecol 20:4408–4420
PubMed
Article
Google Scholar
Sutton JT, Robertson BC, Grueber CE et al (2013) Characterization of MHC class II B polymorphism in bottlenecked New Zealand saddlebacks reveals low levels of genetic diversity. Immunogenetics 65:619–633
CAS
PubMed
Article
Google Scholar
Tajima F (1989) Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 123:585–595
CAS
PubMed
PubMed Central
Google Scholar
Tamura K (1992) Estimation of the number of nucleotide substitutions When there are strong transition-transversion and G+C-content biases. Mol Biol Evol 9:678–687
CAS
PubMed
Google Scholar
Tamura K, Dudley J, Nei M, Kumar S (2007) MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0. Mol Biol Evol 24:1596–1599
CAS
PubMed
Article
Google Scholar
Tompkins DM (2007) Population bottlenecks and avian immunity: implications for conservation. Anim Conserv 10:11–13
Article
Google Scholar
Tompkins DM, Poulin R (2006) Parasites and biological invasions. Biol Invasions New Zeal Ecol Stud 186:67–84
Article
Google Scholar
Tu J, Li D, Li Q et al (2015) Molecular evolutionary analysis of β-defensin peptides in vertebrates. Evol Bioinform 11:105–114
Google Scholar
Turner AK, Begon M, Jackson JA, Paterson S (2012) Evidence for selection at cytokine loci in a natural population of field voles (Microtus agrestis). Mol Ecol 21:1632–1646
CAS
PubMed
Article
Google Scholar
van de Crommenacker J, Komdeur J, Burke T, Richardson DS (2011) Spatio-temporal variation in territory quality and oxidative status: a natural experiment in the Seychelles warbler (Acrocephalus sechellensis). J Anim Ecol 80:668–680
PubMed
PubMed Central
Article
Google Scholar
van Dijk A, Veldhuizen EJ, Haagsman HP (2008) Avian defensins. Vet Immunol Immunopathol 124:1–18
PubMed
Article
CAS
Google Scholar
van Oosterhout C (2009) A new theory of MHC evolution: beyond selection on the immune genes. Proc Biol Sci 276:657–665
PubMed
PubMed Central
Article
CAS
Google Scholar
van Oosterhout C, Joyce DA, Cummings SA et al (2006) Balancing selection, random genetic drift, and genetic variation at the major histocompatibility complex in two wild populations of guppies (Poecilia reticulata). Evolution 60:2562–2574
PubMed
Article
Google Scholar
Van Oosterhout C, Smith AM, Hänfling B et al (2007) The guppy as a conservation model: implications of parasitism and inbreeding for reintroduction success. Conserv Biol 21:1573–1583
PubMed
Google Scholar
Vila C, Sundqvist A-K, Flagstad O et al (2003) Rescue of a severely bottlenecked wolf (Canis lupus) population by a single immigrant. Proc R Soc B Biol Sci 270:91–97
Article
Google Scholar
Vögeli M, Lemus JA, Serrano D et al (2011) An island paradigm on the mainland: host population fragmentation impairs the community of avian pathogens. Proc R Soc B 278:2668–2676
PubMed
PubMed Central
Article
Google Scholar
Wong WSW (2004) Accuracy and power of statistical methods for detecting adaptive evolution in protein coding sequences and for identifying positively selected sites. Genetics 168:1041–1051
CAS
PubMed
PubMed Central
Article
Google Scholar
Wright DJ, Shah NJ, Richardson DS (2014a) Translocation of the Seychelles warbler Acrocephalus sechellensis to establish a new population on Frégate Island, Seychelles. Conserv Evid 11:20–24
Google Scholar
Wright DJ, Spurgin LG, Collar NJ et al (2014b) The impact of translocations on neutral and functional genetic diversity within and among populations of the Seychelles warbler. Mol Ecol 23:2165–2177
PubMed
PubMed Central
Article
Google Scholar
Xiao Y, Hughes AL, Ando J et al (2004) A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins. BMC Genom 5:56
Article
CAS
Google Scholar
Yang D, Biragyn A, Kwak LW, Oppenheim JJ (2002) Mammalian defensins in immunity: more than just microbicidal. Trends Immunol 23:291–296
CAS
PubMed
Article
Google Scholar
Zhu L, Hu Y, Qi D et al (2013) Genetic consequences of historical anthropogenic and ecological events on giant pandas. Ecology 94:2346–2357
PubMed
Article
Google Scholar