Correction to: Cellular and Molecular Neurobiology https://doi.org/10.1007/s10571-019-00770-9

The original version of the article unfortunately contained an error in the unit of the protein concentrations under 'Stereotactic Intraparenchymal Injections' subsection in ‘Methods’ section.

The unit should be ng/μl instead of ng/ml.

Therefore, the sentence should read as follows:

For the claudin-5 expression study, solutions with the following protein concentrations were prepared: 40 ng/μl VEGF (group VEGF alone), 40 ng/μl VEGF and 40 ng/μl PEDF (group VEGF:PEDF 1:1), and 40 ng/μl VEGF and 80 ng/μl PEDF (group VEGF:PEDF 1:2).

Accordingly, the caption of Fig. 1 should be as follows:

Fig. 1
figure 1

The Co-injection of PEDF after VEGF-induced hyperpermeability reduces the paracellular blood–brain barrier disruption. a We wanted to confirm that VEGF induces hyperpermeability in the brain. Therefore, we administered intraparenchymal injection of 40 ng/μl VEGF or CSF to the brain. VEGF did not significantly induce the transcellular extravasation of Evans Blue (expressed as the fold change to CSF, n = 3). However, we recognize that the sample size was likely not large enough to show statistical significance. b Compared to VEGF alone (40 ng/μl), the coadministration of PEDF (40 ng/μl) did not change the Evans Blue extravasation (n = 6). c Shown are representative pictures from the claudin-5 (Cln-5) stained brain samples in mice receiving an intraparenchymal injection of CSF, VEGF, or VEGF + PEDF. Scale bar = 100 μm. d The number of claudin-5-immunoreactive vessels significantly increased after the VEGF + PEDF (40 ng/μl VEGF and 40 ng/μl PEDF for VEGF:PEDF 1:1, n = 11; 40 ng/μl VEGF and 80 ng/μl PEDF for VEGF:PEDF 1:2, n = 9) compared to the 40 ng/μl VEGF-only treatment, indicating an improved paracellular BBB integrity. The data are represented as medians, except for the amount of claudin-5-immunoreactive vessels in VEGF + PEDF 1:2 that is presented as mean ± SD, *p < 0.05

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