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Contrast-Induced Acute Kidney Injury: An Update

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Abstract

Contrast-induced acute kidney injury (CI-AKI) is defined as an abrupt deterioration in renal function associated with the administration of iodinated contrast media. This type of acute kidney injury is frequently encountered as a complication of percutaneous coronary intervention (PCI) and is associated with adverse short- and long-term outcomes including mainly mortality, cardiovascular morbidity and prolongation of hospitalization. The incidence of CI-AKI after PCI ranges from 2 to 20 % according to baseline kidney function. It may also range according to the clinical setting, being higher after emergency PCI. The primary manifestation is a small decline in kidney function, occurring 1 to 3 days after the procedure. Kidney function usually returns to preexisting levels within 7 days. Incidence of acute renal failure requiring dialysis following PCI is rare (<1 %). The present article aims to review up-to-date published data concerning diagnosis, definition, epidemiology and prognosis of this novel in-hospital epidemic.

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  1. University Cardiology Department, Medical School, Democritus University of Thrace, Dragana, GR-68131, Alexandroupolis, Greece

    George Chalikias, Ioannis Drosos & Dimitrios N. Tziakas

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  1. George Chalikias
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  2. Ioannis Drosos
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  3. Dimitrios N. Tziakas
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Correspondence to Dimitrios N. Tziakas.

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Chalikias, G., Drosos, I. & Tziakas, D.N. Contrast-Induced Acute Kidney Injury: An Update. Cardiovasc Drugs Ther 30, 215–228 (2016). https://doi.org/10.1007/s10557-015-6635-0

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