Abstract
Acute kidney injury (AKI) occurs when there is an acute fall in glomerular filtration rate (GFR) resulting in a reduction of kidney function.
The causes of AKI can be categorised as:
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Pre-renal, generally in which decreased renal blood flow results in a drop in GFR
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Intrinsic/intra-renal, in which a disease process causes damage to the kidney itself
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Post-renal, in which a process downstream of the kidney prevents drainage of urine (urinary tract obstruction)
These categories are discussed in more detail below. The classification and treatment of AKI is discussed elsewhere.
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Sluman, C., Gudka, P.M., McCormick, K. (2020). Acute Kidney Injury: Pre-renal, Intra-renal and Post-renal. In: Braund, R. (eds) Renal Medicine and Clinical Pharmacy. Advanced Clinical Pharmacy - Research, Development and Practical Applications, vol 1. Springer, Cham. https://doi.org/10.1007/978-3-030-37655-0_3
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