Skip to main content

Advertisement

SpringerLink
Log in

Lifetime alcohol consumption patterns and young-onset breast cancer by subtype among Non-Hispanic Black and White women in the Young Women’s Health History Study

  • Original Paper
  • Published:
Cancer Causes & Control Aims and scope Submit manuscript

Abstract

Purpose

The role of alcohol in young-onset breast cancer (YOBC) is unclear. We examined associations between lifetime alcohol consumption and YOBC in the Young Women’s Health History Study, a population-based case–control study of breast cancer among Non-Hispanic Black and White women < 50 years of age.

Methods

Breast cancer cases (n = 1,812) were diagnosed in the Metropolitan Detroit and Los Angeles County SEER registry areas, 2010–2015. Controls (n = 1,381) were identified through area-based sampling and were frequency-matched to cases by age, site, and race. Alcohol consumption and covariates were collected from in-person interviews. Weighted multivariable logistic regression was conducted to calculate adjusted odds ratios (aOR) and 95% confidence intervals (CI) for associations between alcohol consumption and YOBC overall and by subtype (Luminal A, Luminal B, HER2, or triple negative).

Results

Lifetime alcohol consumption was not associated with YOBC overall or with subtypes (all ptrend ≥ 0.13). Similarly, alcohol consumption in adolescence, young and middle adulthood was not associated with YOBC (all ptrend ≥ 0.09). An inverse association with triple-negative YOBC, however, was observed for younger age at alcohol use initiation (< 18 years vs. no consumption), aOR (95% CI) = 0.62 (0.42, 0.93). No evidence of statistical interaction by race or household poverty was observed.

Conclusions

Our findings suggest alcohol consumption has a different association with YOBC than postmenopausal breast cancer—lifetime consumption was not linked to increased risk and younger age at alcohol use initiation was associated with a decreased risk of triple-negative YOBC. Future studies on alcohol consumption in YOBC subtypes are warranted.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

Data availability

All authors contributed to the study conception and design. Data analyses were performed by Darek Lucas. The first draft of the manuscript was written by Kelly A. Hirko and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript and assume full responsibility for analyses and interpretation of these data. The datasets analyzed for this study are not publicly available because main study findings are in the process of being analyzed, but can be made available on reasonable request.

Abbreviations

YWHHS:

Young women’s health history study

YOBC:

Young-onset breast cancer

ER:

Estrogen receptor

PR:

Progesterone receptor

HER2:

Human epidermal growth factor 2

TNBC:

Triple-negative breast cancer

aOR:

Adjusted odds ratios

CI:

Confidence intervals

BMI:

Body mass index

NHB:

Non-hispanic black

NHW:

Non-hispanic white

SEER:

Surveillance epidemiology and end results

HHP:

Household percent poverty

SEP:

Socioeconomic position

References

  1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A (2018) Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 68:394–424

    Article  PubMed  Google Scholar 

  2. Heer E, Harper A, Escandor N, Sung H, McCormack V, Fidler-Benaoudia MM (2020) Global burden and trends in premenopausal and postmenopausal breast cancer: a population-based study. Lancet Glob Health 8:e1027–e1037

    Article  PubMed  Google Scholar 

  3. DeSantis CE, Fedewa SA, Goding Sauer A, Kramer JL, Smith RA, Jemal A (2016) Breast cancer statistics, 2015: Convergence of incidence rates between black and white women. CA Cancer J Clin 66:31–42

    Article  PubMed  Google Scholar 

  4. Marie Swanson G, Haslam SZ, Azzouz F (2003) Breast cancer among young African-American women: a summary of data and literature and of issues discussed during the Summit Meeting on Breast Cancer Among African American Women, Washington, DC, September 8–10, 2000. Cancer 97:273–279

    Article  CAS  PubMed  Google Scholar 

  5. Anders CK, Hsu DS, Broadwater G, Acharya CR, Foekens JA, Zhang Y, Wang Y, Marcom PK, Marks JR, Febbo PG, Nevins JR, Potti A et al (2008) Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression. J Clin Oncol Off J Am Soc Clin Oncol 26:3324–3330

    Article  Google Scholar 

  6. Anders CK, Johnson R, Litton J, Phillips M, Bleyer A (2009) Breast cancer before age 40 years. Semin Oncol 36:237–249

    Article  PubMed  PubMed Central  Google Scholar 

  7. Keegan THM, DeRouen MC, Press DJ, Kurian AW, Clarke CA (2012) Occurrence of breast cancer subtypes in adolescent and young adult women. Breast Cancer Res BCR 14:R55

    Article  CAS  PubMed  Google Scholar 

  8. Zhu Y, Aupperlee MD, Haslam SZ, Schwartz RC (2017) Pubertally initiated high-fat diet promotes mammary tumorigenesis in obesity-prone FVB mice similarly to obesity-resistant BALB/c mice. Transl Oncol 10:928–935

    Article  PubMed  PubMed Central  Google Scholar 

  9. Zhu Y, Aupperlee MD, Zhao Y, Tan YS, Kirk EL, Sun X, Troester MA, Schwartz RC, Haslam SZ (2016) Pubertal and adult windows of susceptibility to a high animal fat diet in Trp53-null mammary tumorigenesis. Oncotarget 7:83409–83423

    Article  PubMed  PubMed Central  Google Scholar 

  10. García-Estévez L, Cortés J, Pérez S, Calvo I, Gallegos I, Moreno-Bueno G (2021) Obesity and breast cancer: a paradoxical and controversial relationship influenced by menopausal status. Front Oncol 11:705911

    Article  PubMed  PubMed Central  Google Scholar 

  11. Tamimi RM, Colditz GA, Hazra A, Baer HJ, Hankinson SE, Rosner B, Marotti J, Connolly JL, Schnitt SJ, Collins LC (2012) Traditional breast cancer risk factors in relation to molecular subtypes of breast cancer. Breast Cancer Res Treat 131:159–167

    Article  CAS  PubMed  Google Scholar 

  12. Perou CM, Jeffrey SS, van de Rijn M, Rees CA, Eisen MB, Ross DT, Pergamenschikov A, Williams CF, Zhu SX, Lee JC, Lashkari D, Shalon D et al (1999) Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc Natl Acad Sci USA 96:9212–9217

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, Demeter J, Perou CM et al (2003) Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA 100:8418–8423

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Brenton JD, Carey LA, Ahmed AA, Caldas C (2005) Molecular classification and molecular forecasting of breast cancer: ready for clinical application? J Clin Oncol Off J Am Soc Clin Oncol 23:7350–7360

    Article  CAS  Google Scholar 

  15. Barnard ME, Boeke CE, Tamimi RM (2015) Established breast cancer risk factors and risk of intrinsic tumor subtypes. Biochim Biophys Acta 1856:73–85

    CAS  PubMed  Google Scholar 

  16. Gaudet MM, Press MF, Haile RW, Lynch CF, Glaser SL, Schildkraut J, Gammon MD, Douglas Thompson W, Bernstein JL (2011) Risk factors by molecular subtypes of breast cancer across a population-based study of women 56 years or younger. Breast Cancer Res Treat 130:587–597

    Article  PubMed  PubMed Central  Google Scholar 

  17. Hamajima N, Hirose K, Tajima K, Rohan T, Calle EE, Heath CW, Coates RJ, Liff JM, Talamini R, Chantarakul N, Koetsawang S, Rachawat D et al (2002) Alcohol, tobacco and breast cancer–collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease. Br J Cancer 87:1234–1245

    Article  CAS  PubMed  Google Scholar 

  18. Smith-Warner SA, Spiegelman D, Yaun SS, van den Brandt PA, Folsom AR, Goldbohm RA, Graham S, Holmberg L, Howe GR, Marshall JR, Miller AB, Potter JD et al (1998) Alcohol and breast cancer in women: a pooled analysis of cohort studies. JAMA 279:535–540

    Article  CAS  PubMed  Google Scholar 

  19. Nelson HD, Zakher B, Cantor A, Fu R, Griffin J, O’Meara ES, Buist DSM, Kerlikowske K, van Ravesteyn NT, Trentham-Dietz A, Mandelblatt JS, Miglioretti DL (2012) Risk factors for breast cancer for women aged 40 to 49 years: a systematic review and meta-analysis. Ann Intern Med 156:635–648

    Article  PubMed  PubMed Central  Google Scholar 

  20. Jung S, Wang M, Anderson K, Baglietto L, Bergkvist L, Bernstein L, van den Brandt PA, Brinton L, Buring JE, Eliassen AH, Falk R, Gapstur SM et al (2016) Alcohol consumption and breast cancer risk by estrogen receptor status: in a pooled analysis of 20 studies. Int J Epidemiol 45:916–928

    Article  PubMed  Google Scholar 

  21. Chen WY, Rosner B, Hankinson SE, Colditz GA, Willett WC (2011) Moderate alcohol consumption during adult life, drinking patterns, and breast cancer risk. JAMA 306:1884–1890

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. Garland M, Hunter DJ, Colditz GA, Spiegelman DL, Manson JE, Stampfer MJ, Willett WC (1999) Alcohol consumption in relation to breast cancer risk in a cohort of United States women 25–42 years of age. Cancer Epidemiol Biomark Prev Publ Am Assoc Cancer Res Cosponsored Am Soc Prev Oncol 8:1017–1021

    CAS  Google Scholar 

  23. Kim HJ, Jung S, Eliassen AH, Chen WY, Willett WC, Cho E (2017) Alcohol consumption and breast cancer risk in younger women according to family history of breast cancer and folate intake. Am J Epidemiol 186:524–531

    Article  PubMed  PubMed Central  Google Scholar 

  24. Rohan TE, Jain M, Howe GR, Miller AB (2000) Alcohol consumption and risk of breast cancer: a cohort study. Cancer Causes Control CCC 11:239–247

    Article  CAS  PubMed  Google Scholar 

  25. Hiatt RA, Klatsky AL, Armstrong MA (1988) Alcohol consumption and the risk of breast cancer in a prepaid health plan. Cancer Res 48:2284–2287

    CAS  PubMed  Google Scholar 

  26. Fagherazzi G, Vilier A, Boutron-Ruault M-C, Mesrine S, Clavel-Chapelon F (2015) Alcohol consumption and breast cancer risk subtypes in the E3N-EPIC cohort. Eur J Cancer Prev Off J Eur Cancer Prev Organ ECP 24:209–214

    Article  CAS  Google Scholar 

  27. Althuis MD, Brogan DD, Coates RJ, Daling JR, Gammon MD, Malone KE, Schoenberg JB, Brinton LA (2003) Breast cancers among very young premenopausal women (United States). Cancer Causes Control CCC 14:151–160

    Article  PubMed  Google Scholar 

  28. Kropp S, Becher H, Nieters A, Chang-Claude J (2001) Low-to-moderate alcohol consumption and breast cancer risk by age 50 years among women in Germany. Am J Epidemiol 154:624–634

    Article  CAS  PubMed  Google Scholar 

  29. Ferraroni M, Decarli A, Willett WC, Marubini E (1991) Alcohol and breast cancer risk: a case-control study from northern Italy. Int J Epidemiol 20:859–864

    Article  CAS  PubMed  Google Scholar 

  30. Weiss HA, Brinton LA, Brogan D, Coates RJ, Gammon MD, Malone KE, Schoenberg JB, Swanson CA (1996) Epidemiology of in situ and invasive breast cancer in women aged under 45. Br J Cancer 73:1298–1305

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  31. van’t veer P, Kok FJ, Hermus RJ, Sturmans F (1989) Alcohol dose, frequency and age at first exposure in relation to the risk of breast cancer. Int J Epidemiol 18:511–517

    Article  PubMed  Google Scholar 

  32. Berstad P, Ma H, Bernstein L, Ursin G (2008) Alcohol intake and breast cancer risk among young women. Breast Cancer Res Treat 108:113–120

    Article  PubMed  Google Scholar 

  33. Ntirenganya F, Twagirumukiza JD, Bucyibaruta G, Rugwizangoga B, Rulisa S (2021) Premenopausal breast cancer risk factors and associations with molecular subtypes: a case-control study. Int J Breast Cancer 2021:5560559

    Article  PubMed  PubMed Central  Google Scholar 

  34. O’Brien KM, Sun J, Sandler DP, DeRoo LA, Weinberg CR (2015) Risk factors for young-onset invasive and in situ breast cancer. Cancer Causes Control CCC 26:1771–1778

    Article  PubMed  PubMed Central  Google Scholar 

  35. Hirko KA, Spiegelman D, Willett WC, Hankinson SE, Eliassen AH (2014) Alcohol consumption in relation to plasma sex hormones, prolactin, and sex hormone-binding globulin in premenopausal women. Cancer Epidemiol Biomark Prev Publ Am Assoc Cancer Res Cosponsored Am Soc Prev Oncol 23:2943–2953

    Article  CAS  Google Scholar 

  36. Hirko KA, Chen WY, Willett WC, Rosner BA, Hankinson SE, Beck AH, Tamimi RM, Eliassen AH (2016) Alcohol consumption and risk of breast cancer by molecular subtype: prospective analysis of the nurses’ health study after 26 years of follow-up. Int J Cancer 138:1094–1101

    Article  CAS  PubMed  Google Scholar 

  37. Manthey J, Shield KD, Rylett M, Hasan OSM, Probst C, Rehm J (2019) Global alcohol exposure between 1990 and 2017 and forecasts until 2030: a modelling study. Lancet Lond Engl 393:2493–2502

    Article  Google Scholar 

  38. Kanny D, Naimi TS, Liu Y, Brewer RD (2020) Trends in total binge drinks per adult who reported binge drinking - United States, 2011–2017. MMWR Morb Mortal Wkly Rep 69:30–34

    Article  PubMed  PubMed Central  Google Scholar 

  39. Pollard MS, Tucker JS, Green HD (2020) Changes in adult alcohol use and consequences during the COVID-19 pandemic in the US. JAMA Netw Open 3:e2022942

    Article  PubMed  PubMed Central  Google Scholar 

  40. Velie EM, Marcus LR, Pathak DR, Hamilton AS, DiGaetano R, Klinger R, Gollapudi B, Houang R, Carnegie N, Olson LK, Allen A, Zhang Z, et al. Theory, methods, and operational results of the Young Women’s Health History Study: a study of young-onset breast cancer incidence in Black and White women. Cancer Causes Control CCC 2021;

  41. American Association for Public Opinion Research. Standard Definitions: Final Dispositions of Case Codes and Outcome Rates for Surveys. 9th edition [Internet]. 2016;Available from: http://www.aapor.org/AAPOR_Main/media/publications/Standard-Definitions20169thEditionfinal.pdf

  42. Li Y, Graubard B, Digaetano R (2011) Weighting methods for population-based case-control studies with complex sampling. J R Stat Soc Ser C Appl Stat 60:165–185

    Article  Google Scholar 

  43. National Institute on Alcohol Abuse and Alcoholism. What is a standard drink? [Internet]. Available from: https://www.niaaa.nih.gov/alcohols-effects-health/overview-alcohol-consumption/what-standard-drink

  44. Haytowitz DB, Ahuja JKC, Wu X, Somanchi M, Nickle M, Nguyen QA, Roseland JM, Williams JR, Patterson KY, Li Y, Pehrsson PR. USDA National Nutrient Database for Standard Reference, Legacy Release. [Internet]. 2019 [cited 2021 Apr 13];Available from: https://data.nal.usda.gov/dataset/usda-national-nutrient-database-standard-reference-legacy-release.

  45. World Cancer Research Fund/American Institute for Cancer Research. Diet, Nutrition, Physical Activity and Cancer: a Global Perspective. Continuous Update Project Expert Report [Internet]. 2018; Available from: dietandcancerreport.org

  46. Liu Y, Colditz GA, Rosner B, Berkey CS, Collins LC, Schnitt SJ, Connolly JL, Chen WY, Willett WC, Tamimi RM (2013) Alcohol intake between menarche and first pregnancy: a prospective study of breast cancer risk. J Natl Cancer Inst 105:1571–1578

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  47. Belloni A, Chernozhukov V, Wei Y (2016) Post-selection inference for generalized linear models with many controls. J Bus Econom Statist 34:606–619

    Article  Google Scholar 

  48. Williams LA, Olshan AF, Tse CK, Bell ME, Troester MA (2016) Alcohol intake and invasive breast cancer risk by molecular subtype and race in the Carolina Breast Cancer Study. Cancer Causes Control CCC 27:259–269

    Article  PubMed  Google Scholar 

  49. McDonald JA, Mandel MG, Marchbanks PA, Folger SG, Daling JR, Ursin G, Simon MS, Bernstein L, Strom BL, Norman SA, Malone KE, Weiss LK et al (2004) Alcohol exposure and breast cancer: results of the women’s contraceptive and reproductive experiences study. Cancer Epidemiol Biomark Prev Publ Am Assoc Cancer Res Cosponsored Am Soc Prev Oncol 13:2106–2116

    Article  CAS  Google Scholar 

  50. Claus EB, Schildkraut JM, Thompson WD, Risch NJ (1996) The genetic attributable risk of breast and ovarian cancer. Cancer 77:2318–2324

    Article  CAS  PubMed  Google Scholar 

  51. Lindtner C, Scherer T, Zielinski E, Filatova N, Fasshauer M, Tonks NK, Puchowicz M, Buettner C (2013) Binge drinking induces whole-body insulin resistance by impairing hypothalamic insulin action. Sci Transl Med 5:170ra14

    Article  PubMed  PubMed Central  Google Scholar 

  52. Seitz HK, Maurer B (2007) The relationship between alcohol metabolism, estrogen levels, and breast cancer risk. Alcohol Res Health J Natl Inst Alcohol Abuse Alcohol 30:42–43

    Google Scholar 

  53. Lorenti Garcia C, Mechilli M, Proietti De Santis L, Schinoppi A, Kobos K, Palitti F (2009) Relationship between DNA lesions, DNA repair and chromosomal damage induced by acetaldehyde. Mutat Res 662:3–9

    Article  CAS  PubMed  Google Scholar 

  54. Fan AZ, Russell M, Naimi T, Li Y, Liao Y, Jiles R, Mokdad AH (2008) Patterns of alcohol consumption and the metabolic syndrome. J Clin Endocrinol Metab 93:3833–3838

    Article  CAS  PubMed  Google Scholar 

  55. De Pergola G, Silvestris F (2013) Obesity as a major risk factor for cancer. J Obes 2013:291546

    Article  PubMed  PubMed Central  Google Scholar 

  56. Mørch LS, Johansen D, Thygesen LC, Tjønneland A, Løkkegaard E, Stahlberg C, Grønbaek M (2007) Alcohol drinking, consumption patterns and breast cancer among Danish nurses: a cohort study. Eur J Public Health 17:624–629

    Article  PubMed  Google Scholar 

  57. White AJ, DeRoo LA, Weinberg CR, Sandler DP (2017) Lifetime alcohol intake, binge drinking behaviors, and breast cancer risk. Am J Epidemiol 186:541–549

    Article  PubMed  PubMed Central  Google Scholar 

  58. Sánchez-Bayona R, Gea A, Gardeazabal I, Romanos-Nanclares A, Martínez-González MÁ, Bes-Rastrollo M, Santisteban M, Toledo E. Binge Drinking and Risk of Breast Cancer: Results from the SUN ('Seguimiento Universidad de Navarra’) Project. Nutrients 2020;12.

  59. Longnecker MP, Newcomb PA, Mittendorf R, Greenberg ER, Clapp RW, Bogdan GF, Baron J, MacMahon B, Willett WC (1995) Risk of breast cancer in relation to lifetime alcohol consumption. J Natl Cancer Inst 87:923–929

    Article  CAS  PubMed  Google Scholar 

  60. Liu Y, Nguyen N, Colditz GA (2015) Links between alcohol consumption and breast cancer: a look at the evidence. Womens Health Lond Engl 11:65–77

    Article  CAS  PubMed  Google Scholar 

  61. Colditz GA, Frazier AL (1995) Models of breast cancer show that risk is set by events of early life: prevention efforts must shift focus. Cancer Epidemiol Biomark Prev Publ Am Assoc Cancer Res Cosponsored Am Soc Prev Oncol 4:567–571

    CAS  Google Scholar 

  62. Smith SJ, Deacon JM, Chilvers CE (1994) Alcohol, smoking, passive smoking and caffeine in relation to breast cancer risk in young women. UK National Case-Control Study Group. Br J Cancer 70:112–119

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  63. Swanson CA, Coates RJ, Malone KE, Gammon MD, Schoenberg JB, Brogan DJ, McAdams M, Potischman N, Hoover RN, Brinton LA (1997) Alcohol consumption and breast cancer risk among women under age 45 years. Epidemiol Camb Mass 8:231–237

    Article  CAS  Google Scholar 

  64. Holmberg L, Baron JA, Byers T, Wolk A, Ohlander EM, Zack M, Adami HO (1995) Alcohol intake and breast cancer risk: effect of exposure from 15 years of age. Cancer Epidemiol Biomark Prev Publ Am Assoc Cancer Res Cosponsored Am Soc Prev Oncol 4:843–847

    CAS  Google Scholar 

  65. Potischman N, Swanson CA, Siiteri P, Hoover RN (1996) Reversal of relation between body mass and endogenous estrogen concentrations with menopausal status. J Natl Cancer Inst 88:756–758

    Article  CAS  PubMed  Google Scholar 

  66. Key TJ, Appleby PN, Reeves GK, Roddam A, Dorgan JF, Longcope C, Stanczyk FZ, Stephenson HE, Falk RT, Miller R, Schatzkin A, Allen DS et al (2003) Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women. J Natl Cancer Inst 95:1218–1226

    Article  CAS  PubMed  Google Scholar 

  67. Lahmann PH, Hoffmann K, Allen N, van Gils CH, Khaw K-T, Tehard B, Berrino F, Tjønneland A, Bigaard J, Olsen A, Overvad K, Clavel-Chapelon F et al (2004) Body size and breast cancer risk: findings from the European prospective investigation into cancer and nutrition (EPIC). Int J Cancer 111:762–771

    Article  CAS  PubMed  Google Scholar 

  68. Mendelson J, Mello N, Teoh SK, Ellingboe J (1989) Alcohol effects on luteinizing hormone releasing hormone-stimulated anterior pituitary and gonadal hormones in women. J Pharmacol Exp Ther 250:902–909

    CAS  PubMed  Google Scholar 

  69. Rossi BV, Berry KF, Hornstein MD, Cramer DW, Ehrlich S, Missmer SA (2011) Effect of alcohol consumption on in vitro fertilization. Obstet Gynecol 117:136–142

    Article  PubMed  PubMed Central  Google Scholar 

  70. Anwar MY, Marcus M, Taylor KC (2021) The association between alcohol intake and fecundability during menstrual cycle phases. Hum Reprod 36:2538–2548

    Article  PubMed  PubMed Central  Google Scholar 

  71. García-Closas M, Herbstman J, Schiffman M, Glass A, Dorgan JF (2002) Relationship between serum hormone concentrations, reproductive history, alcohol consumption and genetic polymorphisms in pre-menopausal women: determinants of hormone levels IN pre-menopausal women. Int J Cancer 102:172–178

    Article  PubMed  Google Scholar 

  72. Croezen S, Visscher TLS, ter Bogt NCW, Veling ML, Haveman-Nies A (2009) Skipping breakfast, alcohol consumption and physical inactivity as risk factors for overweight and obesity in adolescents: results of the E-MOVO project. Eur J Clin Nutr 63:405–412

    Article  CAS  PubMed  Google Scholar 

  73. Vågstrand K, Barkeling B, Forslund HB, Elfhag K, Linné Y, Rössner S, Lindroos A-K (2007) Eating habits in relation to body fatness and gender in adolescents—results from the ‘SWEDES’ study. Eur J Clin Nutr 61:517–525

    Article  PubMed  Google Scholar 

  74. Traversy G, Chaput J-P (2015) Alcohol consumption and obesity: an update. Curr Obes Rep 4:122–130

    Article  PubMed  PubMed Central  Google Scholar 

  75. Alcácera MA, Marques-Lopes I, Fajó-Pascual M, Puzo J, Blas Pérez J, Bes-Rastrollo M, Martínez-González MA (2008) Lifestyle factors associated with BMI in a Spanish graduate population: the SUN Study. Obes Facts 1:80–87

    Article  PubMed  PubMed Central  Google Scholar 

  76. Kinney AY, Millikan RC, Lin YH, Moorman PG, Newman B (2000) Alcohol consumption and breast cancer among black and white women in North Carolina (United States). Cancer Causes Control CCC 11:345–357

    Article  CAS  PubMed  Google Scholar 

  77. Jackson CL, Hu FB, Kawachi I, Williams DR, Mukamal KJ, Rimm EB (2015) Black-White differences in the relationship between alcohol drinking patterns and mortality among US men and women. Am J Public Health 105(Suppl 3):S534-543

    Article  PubMed  PubMed Central  Google Scholar 

  78. Collins SE (2016) Associations between socioeconomic factors and alcohol outcomes. Alcohol Res Curr Rev 38:83–94

    Google Scholar 

  79. Gordon NH (2003) Socioeconomic factors and breast cancer in black and white Americans. Cancer Metastasis Rev 22:55–65

    Article  CAS  PubMed  Google Scholar 

  80. Gordon NH (1995) Association of education and income with estrogen receptor status in primary breast cancer. Am J Epidemiol 142:796–803

    Article  CAS  PubMed  Google Scholar 

  81. Thomson CS, Hole DJ, Twelves CJ, Brewster DH, Black RJ, Scottish Cancer Therapy Network (2001) Prognostic factors in women with breast cancer: distribution by socioeconomic status and effect on differences in survival. J Epidemiol Community Health 55:308–315

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  82. Andaya AA, Enewold L, Horner M-J, Jatoi I, Shriver CD, Zhu K (2012) Socioeconomic disparities and breast cancer hormone receptor status. Cancer Causes Control 23:951–958

    Article  PubMed  Google Scholar 

  83. Qin B, Babel RA, Plascak JJ, Lin Y, Stroup AM, Goldman N, Ambrosone CB, Demissie K, Hong C-C, Bandera EV, Llanos AAM (2021) Neighborhood social environmental factors and breast cancer subtypes among black women. Cancer Epidemiol Biomarkers Prev 30:344–350

    Article  CAS  PubMed  Google Scholar 

  84. Gilligan C, Anderson KG, Ladd BO, Yong YM, David M (2019) Inaccuracies in survey reporting of alcohol consumption. BMC Public Health 19:1639

    Article  PubMed  PubMed Central  Google Scholar 

  85. Tan CH, Denny CH, Cheal NE, Sniezek JE, Kanny D (2015) Alcohol use and binge drinking among women of childbearing age - United States, 2011–2013. MMWR Morb Mortal Wkly Rep 64:1042–1046

    Article  PubMed  Google Scholar 

  86. Hulka BS, Stark AT (1995) Breast cancer: cause and prevention. Lancet Lond Engl 346:883–887

    Article  CAS  Google Scholar 

  87. van den Brandt PA, Ziegler RG, Wang M, Hou T, Li R, Adami H-O, Agnoli C, Bernstein L, Buring JE, Chen Y, Connor AE, Eliassen AH et al (2021) Body size and weight change over adulthood and risk of breast cancer by menopausal and hormone receptor status: a pooled analysis of 20 prospective cohort studies. Eur J Epidemiol 36:37–55

    Article  PubMed  Google Scholar 

  88. Chen Y, Liu L, Zhou Q, Imam MU, Cai J, Wang Y, Qi M, Sun P, Ping Z, Fu X (2017) Body mass index had different effects on premenopausal and postmenopausal breast cancer risks: a dose-response meta-analysis with 3,318,796 subjects from 31 cohort studies. BMC Public Health 17:936

    Article  PubMed  PubMed Central  Google Scholar 

  89. Bagnardi V, Rota M, Botteri E, Tramacere I, Islami F, Fedirko V, Scotti L, Jenab M, Turati F, Pasquali E, Pelucchi C, Galeone C et al (2015) Alcohol consumption and site-specific cancer risk: a comprehensive dose–response meta-analysis. Br J Cancer 112:580–593

    Article  CAS  PubMed  Google Scholar 

  90. Cao Y, Willett WC, Rimm EB, Stampfer MJ, Giovannucci EL. Light to moderate intake of alcohol, drinking patterns, and risk of cancer: results from two prospective US cohort studies. BMJ 2015;h4238.

  91. USDA Dietary Guidelines, 2015–2020 [Internet]. Available from: https://health.gov/our-work/food-nutrition/2015-2020-dietary-guidelines/guidelines/appendix-9/

Download references

Acknowledgments

We would like to thank the participants and staff of the Young Women’s Health History Study for their valuable contributions as well as the Detroit and Los Angeles SEER registries for their assistance. The authors assume full responsibility for analyses and interpretation of these data.

Funding

The Young Women’s Health History Study was funded by the National Institutes of Health, National Cancer Institute R01CA136861 (E.M. Velie, Principal Investigator).

Author information

Authors and Affiliations

  1. Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, MI, 48824, USA

    Kelly A. Hirko & Dorothy R. Pathak

  2. Epidemiology Program, Joseph J. Zilber School of Public Health, University of Wisconsin, Milwaukee, WI, USA

    Darek R. Lucas, Lydia M. Post & Ellen M. Velie

  3. Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

    Ann S. Hamilton & Ugonna Ihenacho

  4. Department of Mathematical Sciences, Montana State University, Bozeman, MT, USA

    Nicole Bohme Carnegie

  5. Department of Education, College of Education, Michigan State University, East Lansing, MI, USA

    Richard T. Houang

  6. Department of Family Medicine and Public Health Sciences, Wayne State University School of Medicine and Karmanos Cancer Institute, Detroit, MI, USA

    Kendra Schwartz

  7. Departments of Medicine and Pathology, Medical College of Wisconsin, Milwaukee, WI, USA

    Ellen M. Velie

Authors
  1. Kelly A. Hirko
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Darek R. Lucas
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Dorothy R. Pathak
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Ann S. Hamilton
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Lydia M. Post
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Ugonna Ihenacho
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Nicole Bohme Carnegie
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Richard T. Houang
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Kendra Schwartz
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Ellen M. Velie
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

KH drafted the manuscript text. DL and LM conducted data analyses. DP, AH, NC, RH, KS, LM, and EV contributed to data collection and study methodology. EV and KH were involved with study conceptualization. All authors reviewed and edited the manuscript.

Corresponding author

Correspondence to Kelly A. Hirko.

Ethics declarations

Conflict of interest

The authors have no relevant financial or non-financial interests to disclose.

Ethical approval

This study protocol was approved by the Institutional Review Boards (IRB) at the University of Wisconsin—Milwaukee (UWM), Milwaukee, WI (and the Medical College of Wisconsin deferred to UWM); Michigan State University (MSU), East Lansing, MI; Wayne State University (WSU), Detroit, MI; the Karmanos Cancer Center, Detroit MI; the Michigan Department of Community Health, MI; the University of Southern California (USC) Health Sciences, Los Angeles, CA; the California Committee for the Protection of Human Subjects, CA; and the California Cancer Registry. All study participants provided informed consent.

Disclosure

The collection of cancer incidence data used in this study was supported by the Metropolitan Detroit SEER registry and Epidemiology Research Core at Wayne State University/Karmanos Cancer Institute and by the California Department of Public Health pursuant to California Health and Safety Code Section 103885; Centers for Disease Control and Prevention’s (CDC) National Program of Cancer Registries, under cooperative agreement 5NU58DP006344; the National Cancer Institute’s Surveillance, Epidemiology and End Results Program under contract HHSN261201800032I awarded to the University of California, San Francisco, contract HHSN261201800015I awarded to the University of Southern California, and contract HHSN261201800009I awarded to the Public Health Institute. The ideas and opinions expressed herein are those of the authors and do not necessarily reflect the opinions of the funders.

Informed consent

This study protocol was approved by the Institutional Review Boards at the University of Wisconsin—Milwaukee (UWM), Milwaukee, WI (and the Medical College of Wisconsin deferred to UWM); Michigan State University (MSU), East Lansing, MI; Wayne State University (WSU), Detroit, MI; the Karmanos Cancer Center, Detroit MI; the Michigan Department of Community Health, MI; the University of Southern California (USC) Health Sciences, Los Angeles, CA; the California Committee for the Protection of Human Subjects, CA; and the California Cancer Registry. All study participants provided informed consent.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (DOCX 43 kb)

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hirko, K.A., Lucas, D.R., Pathak, D.R. et al. Lifetime alcohol consumption patterns and young-onset breast cancer by subtype among Non-Hispanic Black and White women in the Young Women’s Health History Study. Cancer Causes Control 35, 377–391 (2024). https://doi.org/10.1007/s10552-023-01801-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10552-023-01801-z

Keywords

Search

Navigation