Skip to main content

Advertisement

Log in

Validating the meta-analytical results on MDM2, CASP8, XRCC3 polymorphisms and breast cancer risk: examination of Hardy–Weinberg Equilibrium

  • Letter to the Editor
  • Published:
Breast Cancer Research and Treatment Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Mao C, Liao RY, Chen Q (2010) Sensitivity analyses including and excluding the HWE-violating studies are required for meta-analyses of genetic association studies. Breast Cancer Res Treat 121:245–246

    Article  PubMed  CAS  Google Scholar 

  2. Sergentanis TN, Economopoulos KP (2010) GSTT1 and GSTP1 polymorphisms and breast cancer risk: a meta-analysis. Breast Cancer Res Treat 121:195–202

    Article  PubMed  CAS  Google Scholar 

  3. Economopoulos KP, Sergentanis TN (2010) Differential effects of MDM2 SNP309 polymorphism on breast cancer risk along with race: a meta-analysis. Breast Cancer Res Treat 120:211–216

    Article  PubMed  Google Scholar 

  4. Sergentanis TN, Economopoulos KP (2010) Association of two CASP8 polymorphisms with breast cancer risk: a meta-analysis. Breast Cancer Res Treat 120:229–234

    Article  PubMed  CAS  Google Scholar 

  5. Economopoulos KP, Sergentanis TN (2010) XRCC3 Thr241Met polymorphism and breast cancer risk: a meta-analysis. Breast Cancer Res Treat 121:439–443

    Article  PubMed  CAS  Google Scholar 

  6. Thakkinstian A, McElduff P, D’Este C, Duffy D, Attia J (2005) A method for meta-analysis of molecular association studies. Stat Med 24:1291–1306

    Article  PubMed  Google Scholar 

  7. Rohlfs RV, Weir BS (2008) Distributions of Hardy-Weinberg equilibrium test statistics. Genetics 180:1609–1616

    Article  PubMed  CAS  Google Scholar 

  8. Yu KD, Rao NY, Chen AX, Fan L, Yang C, Shao ZM (2010) A systematic review of the relationship between polymorphic sites in the estrogen receptor-beta (ESR2) gene and breast cancer risk. Breast Cancer Res Treat (in press)

  9. Schmidt MK, Reincke S, Broeks A, Braaf LM, Hogervorst FB, Tollenaar RA, Johnson N, Fletcher O, Peto J, Tommiska J et al (2007) Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium. Cancer Res 67:9584–9590

    Article  PubMed  CAS  Google Scholar 

  10. Haiman CA, Garcia RR, Kolonel LN, Henderson BE, Wu AH, Le Marchand L (2008) A promoter polymorphism in the CASP8 gene is not associated with cancer risk. Nat Genet 40:259–260 author reply 260–251

    Article  PubMed  CAS  Google Scholar 

  11. Costa S, Pinto D, Pereira D, Rodrigues H, Cameselle-Teijeiro J, Medeiros R, Schmitt F (2007) DNA repair polymorphisms might contribute differentially on familial and sporadic breast cancer susceptibility: a study on a Portuguese population. Breast Cancer Res Treat 103:209–217

    Article  PubMed  CAS  Google Scholar 

  12. Dufloth RM, Costa S, Schmitt F, Zeferino LC (2005) DNA repair gene polymorphisms and susceptibility to familial breast cancer in a group of patients from Campinas, Brazil. Genet Mol Res 4:771–782

    PubMed  CAS  Google Scholar 

  13. Krupa R, Synowiec E, Pawlowska E, Morawiec Z, Sobczuk A, Zadrozny M, Wozniak K, Blasiak J (2009) Polymorphism of the homologous recombination repair genes RAD51 and XRCC3 in breast cancer. Exp Mol Pathol 87:32–35

    Article  PubMed  CAS  Google Scholar 

  14. Breast Cancer Association Consortium (2006) Commonly studied single-nucleotide polymorphisms and breast cancer: results from the Breast Cancer Association Consortium. J Natl Cancer Inst 98:1382–1396

    Article  Google Scholar 

References for Rebuttal letter

  1. Sergentanis TN, Economopoulos KP (2010) Validating the meta-analytical results on MDM2, CASP8, XRCC3 polymorphisms and breast cancer risk: examination of Hardy-Weinberg Equilibrium. Breast Cancer Res Treat

  2. Yu KD, Rao NY, Chen AX, Fan L, Yang C, Shao ZM (2010) A systematic review of the relationship between polymorphic sites in the estrogen receptor-beta (ESR2) gene and breast cancer risk. Breast Cancer Res Treat. doi:10.1007/s10549-010-0891-2

  3. Sergentanis TN, Economopoulos KP (2010) GSTT1 and GSTP1 polymorphisms and breast cancer risk: a meta-analysis. Breast Cancer Res Treat 121:195–202

    Article  PubMed  CAS  Google Scholar 

  4. Mao C, Liao RY, Chen Q (2010) Sensitivity analyses including and excluding the HWE-violating studies are required for meta-analyses of genetic association studies. Breast Cancer Res Treat 121:245–246

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Theodoros N. Sergentanis.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sergentanis, T.N., Economopoulos, K.P. Validating the meta-analytical results on MDM2, CASP8, XRCC3 polymorphisms and breast cancer risk: examination of Hardy–Weinberg Equilibrium. Breast Cancer Res Treat 126, 819–823 (2011). https://doi.org/10.1007/s10549-010-1291-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10549-010-1291-3

Keywords

Navigation