Skip to main content
Log in

Sensitivity analyses including and excluding the HWE-violating studies are required for meta-analyses of genetic association studies

  • Letter to the Editor
  • Published:
Breast Cancer Research and Treatment Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Thakkinstian A, McElduff P, D’Este C, Duffy D, Attia J (2004) A method for meta-analysis of molecular association studies. Stat Med 24:1291–1306

    Article  Google Scholar 

  2. Attia J, Thakkinstian A, D’Este C (2002) Meta-analyses of molecular association studies: methodologic lessons for genetic epidemiology. J Clin Epidemiol 56:297–303

    Article  Google Scholar 

  3. Sergentanis TN, Economopoulos KP (2009) GSTT1 and GSTP1 polymorphisms and breast cancer risk: a meta-analysis. Breast Cancer Res Treat. doi: 10.1007/s10549-009-0520-0

  4. Kim SU, Lee KM, Park SK, Yoo KY, Noh DY, Choe KJ, Ahn SH, Hirvonen A, Kang D (2004) Genetic polymorphism of glutathione S-transferase P1 and breast cancer risk. J Biochem Mol Biol 37:582–585

    CAS  PubMed  Google Scholar 

  5. Ceschi M, Sun CL, Van Den Berg D, Koh WP, Yu MC, Probst-Hensch N (2005) The effect of cyclin D1 (CCND1) G870A polymorphism on breast cancer risk is modified by oxidative stress among Chinese women in Singapore. Carcinogenesis 26:1457–1464

    Article  CAS  PubMed  Google Scholar 

  6. Chang TW, Wang SM, Guo YL, Tsai PC, Huang CJ, Huang W (2006) Glutathione S-transferase polymorphisms associated with risk of breast cancer in southern Taiwan. Breast 15:754–761

    Article  PubMed  Google Scholar 

  7. Lee SA, Fowke JH, Lu W, Ye C, Zheng Y, Cai Q, Gu K, Gao YT, Shu XO, Zheng W (2008) Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk. Am J Clin Nutr 87:753–760

    CAS  PubMed  Google Scholar 

  8. Sakoda LC, Blackston CR, Xue K, Doherty JA, Ray RM, Lin MG, Stalsberg H, Gao DL, Feng Z, Thomas DB et al (2008) Glutathione S-transferase M1 and P1 polymorphisms and risk of breast cancer and fibrocystic breast conditions in Chinese women. Breast Cancer Res Treat 109:143–155

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Q. Chen.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mao, C., Liao, R.Y. & Chen, Q. Sensitivity analyses including and excluding the HWE-violating studies are required for meta-analyses of genetic association studies. Breast Cancer Res Treat 121, 245–246 (2010). https://doi.org/10.1007/s10549-009-0605-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10549-009-0605-9

Keywords

Navigation