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Tea polyphenols-loaded nanocarriers: preparation technology and biological function

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Abstract

Tea polyphenols (TP) have various biological functions including anti-oxidant, anti-bacterial, anti-apoptotic, anti-inflammatory and bioengineered repair properties. However, TP exhibit poor stability and bioavailability in the gastrointestinal tract. Nanoencapsulation techniques can be used to protect TP and to uphold their original characteristics during processing, storage and digestion, improve their physiochemical properties and enhance their health promoting effects. Nano-embedded TP show higher antioxidant, antibacterial and anticancer properties than TP, allowing TP to play a better role in bioengineering restoration after embedding. In this review, recent advances in nanoencapsulation of TP with biopolymeric nanocarriers (polysaccharides and proteins), lipid-based nanocarriers and innovative developments in preparation strategies were mainly discussed. Additionally, the strengthening biological functions of stability and bioavailability, antioxidant, antibacterial, anticancer activities and bioengineering repair properties activities after the nano-embedding of TP have been considered. Finally, further studies could be conducted for exploring the application of nanoencapsulated systems in food for industrial applications.

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Funding

This work was financially supported by Research Startup Fund of Ningbo University (027-422012002), Zhejiang Provincial Natural Science Foundation of China (LY19C200006), and Ningbo Natural Science Foundation (2019A610433).

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WZ wrote the manuscript and draw diagrams. YL contributed to revising the manuscript, and supervising the work. XZ, ZW and PW helped revise this article. The authors read and approved the final manuscript.

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Correspondence to Yanan Liu.

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The authors have declared no conflict of interest.

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Zhang, W., Liu, Y., Zhang, X. et al. Tea polyphenols-loaded nanocarriers: preparation technology and biological function. Biotechnol Lett 44, 387–398 (2022). https://doi.org/10.1007/s10529-022-03234-1

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  • DOI: https://doi.org/10.1007/s10529-022-03234-1

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