The dynamics of microbial biofilm formation by standard strain and by clinical strains of uropathogenic coliform bacteria was investigated in vitro and the effect of sublethal concentrations of the polymer compound polyazolidinammonium modified with iodine hydrate ions on the initial stages of biofilm formation was assessed. Treatment of immunological plate wells with the polymeric compound prevented film formation, especially in case of clinical E. coli strain carrying FimH virulence gene.
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Al-Bayati BM, Glinskaya EV, Nechaeva OV, Luneva IO. Genotypic detection of FIMH virulence gene in uropathogenic Escherichia coli (UPEC) isolated from urinary tract infection. Izv. Dagestansk. Gos. Ped. Univer. Estesstv. Tochnye Nauki. 2015;(3):52-55. Russian.
Gabrielyan NI, Gorskaya EM, Romanova NI, Tsirulnikova OM. Nosocomial infection and microbial biofilms in surgery. Vestn. Transplantol. Isskustv. Organov. 2012;14(3):83-91. Russian.
Gostev VV, Sidorenko SV. Bacterial biofilms and infections. Zh. Infektol. 2010;2(3):4-15. Russian.
Mikhailova ES, Chervinets YuV, Chervinets VM, Gavrilova OA, Samoukina AM. Biofilm formation by microorganisms isolated from the upper gastrointestinal tract of patients with chronic cholecystitis and cholelithiasis. Uspekhi Sovremen. Estestvoznaniya. 2009;(7):76-77. Russian.
Nechaeva OV, Tikhomirova EI, Zayarsky DA, Vakaraeva MM. Antimicrobial activity of polyazolidinammonium, modified with hydrate-ions of iodine. Zh. Mikrobiol., Epidemiol. Immunobiol. 2015;(3):88-92. Russian.
Oleskin AV, Botvinko IV, Tsavkelova EA. Colonial organization and intercellular communication in microorganisms. Microbiology (Mikrobiologiya). 2000;69(3):309-327.
Tets VV. Microorganisms and Antibiotics. Infections of the Skin, Soft Tissues, Bones, and Joints. St. Petersburg, 2006. Russian.
De Cremer K, Delattin N, De Brucker K, Peeters A, Kucharíková S, Gerits E, Verstraeten N, Michiels J, Van Dijck P, Cammue BP, Thevissen K. Oral administration of the broadspectrum antibiofilm compound toremifene inhibits Candida albicans and Staphylococcus aureus biofilm formation in vivo. Antimicrob. Agents Chemother. 2014;58(12):7606-7610.
De Cremer K, Lanckacker E, Cools TL, Bax M, De Brucker K, Cos P, Cammue BP, Thevissen K. Artemisinins, new miconazole potentiators resulting in increased activity against Candida albicans biofilms. Antimicrob. Agents Chemother. 2015;59(1):421-426.
Delattin N, De Brucker K, Vandamme K, Meert E, Marchand A, Chaltin P, Cammue BP, Thevissen K. Repurposing as a means to increase the activity of amphotericin B and caspofungin against Candida albicans biofilms. Antimicrob. Chemother. 2014;69(4):1035-1044.
Niveditha S, Pramodhini S, Umadevi S, Kumar S, Stephen S. The isolation and the biofilm formation of uropathogens in the patients with catheter associated UTIs. J. Clin. Diagn. Res. 2012;6(9):1478-1482.
Ponnusamy P, Nagappan R. Extended spectrum beta-lactamase, biofilm-producing uropathogenic pathogens and their antibiotic susceptibility patterns from urinary tract infection — an overview. Int. J. Microbiol. Res. 2013;4(2):101-118.
Taff HT, Mitchell KF, Edward JA, Andes DR. Mechanisms of Candida biofilm drug resistance. Future Microbiol. 2013;8(10):1325-1337.
Wolcott RD, Rhoads DD, Dowd SE. Biofilms and chronic wound inflammation. J. Wound Care. 2008;17(8):333-341.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 162, No. 12, pp. 753-755, December, 2016
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Nechaeva, O.V., Tikhomirova, E.I., Zayarsky, D.A. et al. Anti-Biofilm Activity of Polyazolidinammonium Modified with Iodine Hydrate Ions against Microbial Biofilms of Uropathogenic Coliform Bacteria. Bull Exp Biol Med 162, 781–783 (2017). https://doi.org/10.1007/s10517-017-3712-3
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DOI: https://doi.org/10.1007/s10517-017-3712-3