We studied the relationship between the risk of chronic heart disease and FMO3 gene polymorphism E158K analyzed by PCR and restriction fragment length polymorphism (RFLP) analysis. The homozygous 158KK genotype of FMO3 gene is associated with high risk of chronic heart disease in women, but not in men. FMO3 gene polymorphism E158K is a significant predictor of predisposition to chronic heart disease in women.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 159, No. 6, pp. 754–757, June, 2015
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Bushueva, O.Y., Bulgakova, I.V., Ivanov, V.P. et al. Association of Flavin Monooxygenase Gene E158K Polymorphism with Chronic Heart Disease Risk. Bull Exp Biol Med 159, 776–778 (2015). https://doi.org/10.1007/s10517-015-3073-8
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DOI: https://doi.org/10.1007/s10517-015-3073-8