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Lymphocyte Subpopulations and Cytokine Levels in Experimental Hyperhomocysteinemia

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Bulletin of Experimental Biology and Medicine Aims and scope

Moderate exogenous hyperhomocysteinemia is associated with an increase in lymphocyte count (mainly at the expense of cytotoxic T cells), a 2-fold drop of the immunoregulatory index, and increase in TNF-α, IFN-γ, and IL-17α concentrations in the serum and in mononuclear cells. Homocysteine concentration in the mononuclears remains unchanged.

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Authors and Affiliations

  1. Chita State Medical Academy, Chita, Russia

    E. V. Fefelova, P. P. Tereshkov, A. A. Dutov & N. N. Tsybikov

Authors
  1. E. V. Fefelova
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  2. P. P. Tereshkov
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  3. A. A. Dutov
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  4. N. N. Tsybikov
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Corresponding author

Correspondence to E. V. Fefelova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 159, No. 3, pp. 336-338, March, 2015

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Fefelova, E.V., Tereshkov, P.P., Dutov, A.A. et al. Lymphocyte Subpopulations and Cytokine Levels in Experimental Hyperhomocysteinemia. Bull Exp Biol Med 159, 358–360 (2015). https://doi.org/10.1007/s10517-015-2962-1

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  • DOI: https://doi.org/10.1007/s10517-015-2962-1

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