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Role of JNK and Contribution of p53 into Growth Potential of Mesenchymal Progenitor Cells In Vitro

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Bulletin of Experimental Biology and Medicine Aims and scope

Specifi c JNK and p53 inhibitors stimulated the formation of fi broblast colonies (CFU-F) and clusters (ClFU-F) and increased proliferative activity of mesenchymal progenitor cells. No effects of inhibitors of JNK and p53 on differentiation of progenitor elements were revealed.

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References

  1. H. Akita, J. U. Marquardt, M. E. Durkin еt аl., Cancer Res., 74, No. 20, 5903-5913 (2014).

    Article  CAS  PubMed  Google Scholar 

  2. C. Bergantinos, M. Corominas, F. Serras, Development, 137, No. 7, 1169-1179 (2010).

    Article  CAS  PubMed  Google Scholar 

  3. L. Du, C. S. Lyle, T. B. Obey еt аl., J. Biol. Chem., 279, No. 12, 11 957-11 966 (2004).

  4. A. M. Dygai, G. N. Zyuz’kov, V. V. Zhdanov et al., Bull. Exp. Biol. Med., 148, No. 1, 120-125 (2009).

    Article  CAS  PubMed  Google Scholar 

  5. A. M. Dygai, G. N. Zyuz’kov, V. V. Zhdanov et al., Stem Cell Rev., 9, No. 2, 140-147 (2013).

    Article  CAS  PubMed  Google Scholar 

  6. E. C. Georgiadi, G. S. Dimtsas, T. P. Vassilakopoulos еt аl., Leuk. Lymphoma, 6, 1-7 (2014).

    Google Scholar 

  7. E. D. Goldberg, A. M. Dygai, G. N. Zyuz’kov, V. V. Zhdanov, Bull. Exp. Biol. Med., 144, No. 6, 802-805 (2007).

    Article  CAS  PubMed  Google Scholar 

  8. E. D. Goldberg, A. M. Dygai, G. N. Zyuz’kov et al., Bull. Exp. Biol. Med., 143, No. 4, 548-551 (2007).

    Article  CAS  PubMed  Google Scholar 

  9. E. A. Komarova, L. Diatchenko, O. W. Rokhlin еt аl., Oncogene, 17, No. 9, 1089-1096 (1998).

    Article  CAS  PubMed  Google Scholar 

  10. A. M. Manning and R. J. Davis, Nat. Rev. Drug Discov., 2, No. 7, 554-565 (2003).

    Article  CAS  PubMed  Google Scholar 

  11. M. Qi, J. Zhang, W. Zeng, X. Chen, Biochim. Biophys. Acta, 1839, No. 1, 62-69 (2014).

    Article  CAS  PubMed  Google Scholar 

  12. W. Song, Y. Ma, J. Wang еt аl., Cancer Res., 74, No. 9, 2444-2454 (2014).

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  13. G. N. Zyuz’kov, M. G. Danilets, A. A. Ligacheva еt аl., Bull. Exp. Biol. Med., 157, No. 4, 436-439 (2014).

    Article  PubMed  Google Scholar 

  14. G. N. Zyuz’kov, M. G. Danilets, A. A. Ligacheva еt аl., Bull. Exp. Biol. Med.,156, No. 4, 556-559 (2014).

    Article  PubMed  Google Scholar 

  15. G. N. Zyuz’kov, V. V. Zhdanov, A. M. Dygai, E. D. Gol’dberg, Bull. Exp. Biol. Med., 144, No. 6, 840-845 (2007).

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia

    G. N. Zyuz’kov, V. V. Zhdanov, E. V. Udut, L. A. Miroshnichenko, M. G. Danilets, E. V. Simanina, E. S. Trofimova, A. V. Chaikovskii, V. I. Agafonov, E. Yu. Sherstoboev, M. Yu. Minakova, Ya. V. Burmina, V. V. Udut & A. M. Dygai

  2. Tomsk State University, Tomsk, Russia

    G. N. Zyuz’kov & V. V. Udut

Authors
  1. G. N. Zyuz’kov
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  2. V. V. Zhdanov
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  3. E. V. Udut
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  4. L. A. Miroshnichenko
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  5. M. G. Danilets
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  6. E. V. Simanina
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  7. E. S. Trofimova
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  8. A. V. Chaikovskii
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  9. V. I. Agafonov
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  10. E. Yu. Sherstoboev
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  11. M. Yu. Minakova
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  12. Ya. V. Burmina
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  13. V. V. Udut
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  14. A. M. Dygai
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Corresponding author

Correspondence to G. N. Zyuz’kov.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 159, No. 2, pp. 205-208, February, 2015

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Zyuz’kov, G.N., Zhdanov, V.V., Udut, E.V. et al. Role of JNK and Contribution of p53 into Growth Potential of Mesenchymal Progenitor Cells In Vitro . Bull Exp Biol Med 159, 245–247 (2015). https://doi.org/10.1007/s10517-015-2933-6

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  • DOI: https://doi.org/10.1007/s10517-015-2933-6

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