Here we performed individual evaluation of the oxidative stress index that serves as an integral criterion for the balance of LPO–antioxidant defense system in women with endocrine pathology (type 1 diabetes mellitus and infertility with hyperprolactinemia). The state of the LPO–antioxidant defense system was estimated from blood levels of LPO substrates with conjugated double bonds, conjugated dienes, ketodienes, conjugated trienes, thiobarbituric acid-reactive substances, retinol, α-tocopherol, reduced and oxidized glutathione, and SOD activity. The use of this oxidative stress index allowed us to diagnose oxidative stress in female patients with endocrine pathology.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 157, No. 6, pp. 680-683, June, 2014
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Kolesnikova, L.I., Semyonova, N.V., Grebenkina, L.A. et al. Integral Indicator of Oxidative Stress in Human Blood. Bull Exp Biol Med 157, 715–717 (2014). https://doi.org/10.1007/s10517-014-2649-z
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DOI: https://doi.org/10.1007/s10517-014-2649-z