Skip to main content
Log in

Functional and Metabolic Changes in the Brain in Neuropathic Pain Syndrome against the Background of Chronic Epidural Electrostimulation of the Spinal Cord

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Changes in functional and metabolic activities of the brain were evaluated by EEG and positron-emission/computer tomography with 18F-fluorodeoxyglucose in patients with neuropathic pain syndrome previous to and 3 months after implantation of a system for chronic epidural spinal cord stimulation. In most cases, the use of a nerve stimulator was followed by alleviation of neuropathic pain and partial normalization of functional and metabolic activities of brain structures responsible for pain perception, emotiogenic, behavioral, and autonomic responses.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. N. A. Krupina, N. N. Khlebnikova, I. N. Orlova, et al., Bull. Exp. Biol. Med., 149, No. 4, 479-784 (2010).

    CAS  PubMed  Google Scholar 

  2. V. A. Shabalov and E. D. Isagulyan, Vopr. Neyrokhir., No. 4, 11-17 (2005).

  3. G. Barolat, Arch. Med. Res., 31, No. 3, 258-262 (2000).

    Article  CAS  PubMed  Google Scholar 

  4. K. Kumar, R. S. Taylor, L. Jacques, et al., Pain, 132, Nos. 1-2, 179-188 (2007).

    Article  PubMed  Google Scholar 

  5. S. Nagamachi, S. Fujita, R. Nishii, et al., Ann. Nucl. Med., 20, No. 4, 303-310 (2000).

    Article  Google Scholar 

  6. R. B. North, D. H. Kidd, F. Farrokhi, and S. A. Piantadosi, Neurosurgery, 56, No. 1, 98-106 (2005).

    PubMed  Google Scholar 

  7. R. Peyron, B. Laurent, and L. Garcia-Larrea, Neurophysiol. Clin., 30, No. 5, 263-288 (2000).

    Article  CAS  PubMed  Google Scholar 

  8. J. Sarnthein and D. Jeanmonod, Neuroimage, 39, No. 4, 1910-1917 (2008).

    Article  PubMed  Google Scholar 

  9. M. Visocchi, G. M. Della Pepa, G. Esposito, et al., Stereotact. Funct. Neurosurg., 89, No. 5, 263-274 (2011).

    Article  PubMed  Google Scholar 

  10. E. J. Yoon, Y. K. Kim, H. I. Shin, et al., Brain Res., 1540, 64-73 (2013).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A. A. Sufianov.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 157, No. 4, pp. 458-462, April, 2014

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sufianov, A.A., Shapkin, A.G., Sufianova, G.Z. et al. Functional and Metabolic Changes in the Brain in Neuropathic Pain Syndrome against the Background of Chronic Epidural Electrostimulation of the Spinal Cord. Bull Exp Biol Med 157, 462–465 (2014). https://doi.org/10.1007/s10517-014-2591-0

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-014-2591-0

Keywords

Navigation