Skip to main content
Log in

Immunolocation of Cystationine β-Synthase in Cerebral Pontile Nuclei in Humans

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

The immunolocation of cystationine β-synthase in the motor, sensitive, and autonomic nuclei of the cerebral pons was studied on the material from 8 healthy men aged 18-44 years dead from traumas not involving the CNS. The motor nuclei contained numerous large intensely stained cells, while the sensitive and autonomic nuclei contained many small neurons with low levels of cystationine β-synthase marker. However, cells with intense reaction were found among small neurons. They were located mainly at the nuclear periphery, between the nuclei or between the nuclei and conduction tracts. The content of immunopositive neurons in the studied nuclei varied from 2 to 14%. The level of these cells in motor nuclei was 3-4-fold higher than in sensitive and autonomic nuclei.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. V. V. Amunts, Arkh. Anat. Gistol. Embriol., 51, No. 7, 25-29 (1976).

    Google Scholar 

  2. E. V. Gerasimova, G. F. Sitdikova, and A. L. Zefirov, Neirokhimiya, 25, Nos. 1-2, 138-145 (2008).

  3. A. E. Kotsyuba and V. M. Chertok, Tikhookeansk. Med. Zh., No. 4, 43-46 (2010).

  4. S. Carballal, M. Trujillo, E. Cuevasanta, et al., Free Radic. Biol. Med., 50, No. 1, 196-205 (2011).

    Article  PubMed  CAS  Google Scholar 

  5. K. Eto, M. Ogasawara, K. Umemura, et al., J. Neurosci., 22, No. 9, 3386-3391 (2002).

    PubMed  CAS  Google Scholar 

  6. M. A. Garcia-Bereguiain, A. K. Samhan-Arias, F. J. Martin-Romero, et al., Antioxid. Redox Signal, 10, No. 1, 31-42 (2008).

    Article  PubMed  CAS  Google Scholar 

  7. P. Kamoun, Amino Acid, 26, No. 3, 243-254 (2004).

    Article  CAS  Google Scholar 

  8. H. Kimura, Biochem. Biophys. Res. Commun., 267, No. 1, 129-133 (2000).

    Article  PubMed  CAS  Google Scholar 

  9. A. K. Samhan-Arias, M. A. Garcia-Bereguiain, and C. Gutierrez-Merino, Biochem. Biophys. Res. Commun., 388, No. 4, 718-722 (2009).

    Article  PubMed  CAS  Google Scholar 

  10. C. Szaby, Nat. Rev., 6, No. 11, 917-935 (2007).

    Article  Google Scholar 

  11. S. Taoka and R. Banerjee, J. Inorg. Biochem., 87, No. 4, 245-251 (2001).

    Article  PubMed  CAS  Google Scholar 

  12. M. W. Warenycia, L. R. Goodwin, C. G. Benishin, et al., Biochem. Pharmacol., 38, No. 6, 973-981 (1989).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A. E. Kotsyuba.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 155, No. 2, pp. 247-250, February, 2013

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kotsyuba, A.E., Chertok, V.M. Immunolocation of Cystationine β-Synthase in Cerebral Pontile Nuclei in Humans. Bull Exp Biol Med 155, 277–279 (2013). https://doi.org/10.1007/s10517-013-2131-3

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-013-2131-3

Key Words

Navigation