Experiments with passive transfer of immunocompetent cell and serum demonstrated suppression of tumor growth after transfer of splenocytes from animals immunized with Trypanosoma cruzi. The nonspecific constituent of antitumor effect of immunocompetent cells was detected. The previously reported oncoprotective effect of mucins 2 and 3 was not confirmed.
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A. V. Zenina, E. G. Kravtsov, Batmonkh Zetsegsaikhan, et al., Bull. Exp. Biol. Med., 145, No. 3, 352–354 (2008).
V. D. Kallinikova, Antitumor Effects of Flagellar Protozoon T. Cruzi [in Russian], Tula (2004).
Batmonkh Zetsegsaikhan, V. D. Kallinikova, L. V. Pakhorukova, et al., Bull. Exp. Biol., 142, No. 4, 470–473 (2006).
L. A. Sheklakova, V. D. Kallinikova, and L. P. Karpenko, Ibid., 135, No. 1, 89–92 (2003).
A. A. Yarilin, Fundamentals of Immunology [in Russian], Moscow (1999).
C. Junqueira, B. Caetano, D. C. Bartholomeu, et al., Exp. Rev. Mol. Med., 12, e29 (2010).
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 154, No. 12, pp. 730–732, December, 2012
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Zhigunova, A.V., Kravtsov, E.G., Yashina, N.V. et al. Effects of Specific Antibodies and Immunocompetent Cells on Tumor Growth in Passive Transfer Experiment. Bull Exp Biol Med 154, 762–764 (2013). https://doi.org/10.1007/s10517-013-2050-3
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DOI: https://doi.org/10.1007/s10517-013-2050-3