Comparative morphological study of the placentas was carried out in women with pregnancy aggravated by the development of pre-eclampsia. Immunohistochemical methods showed increased expression of endoglin (CD105) and VEGFR1 in all placental structures. The intensity of endoglin and VEGFR1 expression was maximum in the syncytiotrophoblast and extravillous cytotrophoblast cells in severe pre-eclampsia.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 154, No. 8, pp. 257–261, August, 2012
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Shchyogolev, A.I., Dubova, E.A., Pavlova, K.A. et al. Expression of Antiangiogenic Factors in the Placental Structures in Pre-Eclampsia. Bull Exp Biol Med 154, 287–291 (2012). https://doi.org/10.1007/s10517-012-1932-0
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DOI: https://doi.org/10.1007/s10517-012-1932-0