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Excretion of Compound M-11 and Its Metabolites with Urine and Feces in Rats

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The excretion of compound M-11 and its metabolites with the urine and feces was studied in rats after intraperitoneal and oral administration in a dose of 25 mg/kg. Experiments showed that 1% metabolites were detected in excretions over 24 h irrespective of the route of administration, while the initial compound was not found even in trace amounts.

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References

  1. A. O. Viglinskaya, G. B. Kolyvanov, A. A. Litvin, et al., Byull. Eksp. Biol. Med., 145, No. 4, 418-420 (2008).

    Article  Google Scholar 

  2. S. B. Seredenin, A. O. Viglinskaya, G. B. Kolyvanov, et al., Eksp. Klin. Farmakol., 70, No. 2, 59-64 (2007).

    PubMed  CAS  Google Scholar 

  3. T. Andersson, J. O. Miners, M. E. Veronese, and D. J. Birkett, Brit. J. Pharmacol., 37, No. 6, 597-604 (1994).

    Article  CAS  Google Scholar 

  4. M. Hongo, S. Ohara, Y. Hirasawa, et al., Dig. Dis. Sci., 37, No. 6, 882-890 (1992).

    Article  PubMed  CAS  Google Scholar 

  5. R. H. Levy et al., eds., Metabolic Drug Interactions, Philadelphia (2000).

  6. V. W. Steinijans, R. Huber, M. Hartmann, et al., Int. J. Clin. Pharmacol. Ther., 32, No. 8, 385-399 (1994).

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Laboratory of Pharmacokinetics, V. V. Zakusov Institute of Pharmacology, Russian Academy of Medical Sciences, Moscow, Russia

    D. V. Bastrygin, A. O. Viglinskaya, G. B. Kolyvanov, A. A. Litvin, P. O. Bochkov, T. Ya. Mozhaeva & V. P. Zherdev

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  1. D. V. Bastrygin
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  2. A. O. Viglinskaya
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  3. G. B. Kolyvanov
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  4. A. A. Litvin
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  5. P. O. Bochkov
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  6. T. Ya. Mozhaeva
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  7. V. P. Zherdev
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Corresponding author

Correspondence to D. V. Bastrygin.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 153, No. 5, pp. 664-666, May, 2012

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Bastrygin, D.V., Viglinskaya, A.O., Kolyvanov, G.B. et al. Excretion of Compound M-11 and Its Metabolites with Urine and Feces in Rats. Bull Exp Biol Med 153, 707–709 (2012). https://doi.org/10.1007/s10517-012-1805-6

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  • DOI: https://doi.org/10.1007/s10517-012-1805-6

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