Study of the early embryogenesis process based on the previously suggested scheme of epithelial cambial cell work has shown that cambial (or stem) cells originate from the primary ectoderm and intensely express RhoA protein and slightly express Src kinase. This explains their stem properties and the absence of differentiation. Primary sex cells are separated stem cells getting into an environment which expresses (to a certain measure) Src kinase in them and causes their polarization and specialization. In order to induce differentiation of cambial cells in a certain direction, expression of Src kinase should be stimulated to the needed degree in each tissue.
Similar content being viewed by others
References
B. Alberts, D. Bray, J. Lewis, et al., Molecular Biology of Cell [in Russian], Moscow (1994).
S. Gilbert, Developmental Biology [in Russian], Moscow (1993).
A. P. Dyban, Early Development of Mammals [in Russian], Leningrad (1988).
T. M. Yavisheva and S. D. Shcherbakov, Uspekhi Gerontol., 22, No. 4, 605-613 (2009).
M. Conti, M. Hsieh, J. Y. Park, and Y. Q. Su, Mol. Endocrinol., 20, No. 4, 715-723 (2006).
M. P. De Miguel, F. Arnalich Montiel, P. Lopez Iglesias, et al., Int. J. Dev. Biol., 53, Nos. 8-10, 1529-1540 (2009).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 153, No. 1, pp. 94-97, January, 2012
Rights and permissions
About this article
Cite this article
Yavisheva, T.M., Shcherbakov, S.D. On the Common Mechanisms of Cambial Somatic and Sex Cells Proliferation and the Notion of the Cambial Cells. Bull Exp Biol Med 153, 82–85 (2012). https://doi.org/10.1007/s10517-012-1649-0
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-012-1649-0