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Efficiency of Structurally Different Antioxidants in Combined Myocardial Damage in Mice

  • Pharmacology and Toxicology
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Bulletin of Experimental Biology and Medicine Aims and scope

Cardioprotective effects of derivatives of 3-hydroxypyridine, benzimidazole, and a peptide substance were studied on the model of combined damage to the myocardium (catecholamines and physical exercises) in mice. The most pronounced antioxidant and cardioprotective effects were produced by 3-hydroxypyridine acetylcysteinate (50 mg/kg), benzimidazole derivative Be-2m (50 mg/kg), and peptide substance γ-glutamyl histamine (1 mg/kg).

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Correspondence to M. N. Zamotaeva.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 152, No. 9, pp. 286–289, September, 2011

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Zamotaeva, M.N., Inchina, V.I. & Chairkin, I.N. Efficiency of Structurally Different Antioxidants in Combined Myocardial Damage in Mice. Bull Exp Biol Med 152, 318–320 (2012). https://doi.org/10.1007/s10517-012-1517-y

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  • DOI: https://doi.org/10.1007/s10517-012-1517-y

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