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Effect of Meadowsweet (Filipendula vulgaris) Extract on Bioenergetics of the Brain during Experimental Posthypoxic Encephalopathy

  • Pharmacology and Toxicology
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Bulletin of Experimental Biology and Medicine Aims and scope

We studied the effect of Filipendula vulgaris aqueous extract on mitochondrial energy production system in the brain of rats with posthypoxic encephalopathy developing 19 days after hypoxic injury. Filipendula extract more effectively than valerian extract improved kinetic characteristics of respiratory activity of mitochondria, increased substrate oxidation–phosphorylation coupling, and inhibited LPO.

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Authors and Affiliations

  1. Department of Pharmacology, Siberian State Medical University, Tomsk, Russia

    A. I. Vengerovsky

  2. Laboratory of Phytopharmacology, Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia

    N. I. Suslov & A. V. Kaygorodsev

Authors
  1. A. I. Vengerovsky
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  2. N. I. Suslov
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  3. A. V. Kaygorodsev
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Corresponding author

Correspondence to A. I. Vengerovsky.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 151, No. 4, pp. 401–405, April, 2011

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Vengerovsky, A.I., Suslov, N.I. & Kaygorodsev, A.V. Effect of Meadowsweet (Filipendula vulgaris) Extract on Bioenergetics of the Brain during Experimental Posthypoxic Encephalopathy. Bull Exp Biol Med 151, 421 (2011). https://doi.org/10.1007/s10517-011-1346-4

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  • DOI: https://doi.org/10.1007/s10517-011-1346-4

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