Light microscopic examination of the hippocampus was carried out in young rats (intact and injected with propofol and mexidol according to different protocols). Propofol had a negative effect on hippocampal neurons causing an almost 2-fold increase in the count of modified cells in comparison with the normal level. Mexidol effectively corrected these shifts.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 149, No. 4, pp. 457–459, April, 2010
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Dubovay, T.K., Lobov, M.A., Dreval, A.A. et al. Histo- and Cytoarchitectonics of the Hippocampus in Young Rats Injected with Propofol and Mexidol. Bull Exp Biol Med 149, 471–473 (2010). https://doi.org/10.1007/s10517-010-0973-5
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DOI: https://doi.org/10.1007/s10517-010-0973-5