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Mesenchymal Cells of the Deciduous Tooth Pulp: Cytophenotype and Initial Evaluation of Possibility of Their Use in Bone Tissue Engineering

  • Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Cultures of mesenchymal cells from human deciduous tooth pulp were derived. The phenotype and capacity to osteogenic and adipogenic differentiation of these cells are close to those of bone marrow mesenchymal stem cells. Deciduous tooth pulp mesenchymal cells populate biodegradable polylactide scaffolds and hence, can be used for the creation of tissue engineering transplants for bone defect repair. Storage of decidual tooth pulp mesenchymal cells in the stem cell cryobanks together with umbilical blood will appreciably extent the periods of age for collection of juvenile autologous stem cells for use throughout the life span.

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Authors and Affiliations

  1. V. N. Orekhovich Institute of Biomedical Chemistry, the Russian Academy of Medical Sciences, Moscow, Russia

    I. V. Vakhrushev, Yu. G. Suzdaltseva, V. V. Burunova, P. A. Karalkin, A. Yu. Lupatov & K. N. Yarygin

Authors
  1. I. V. Vakhrushev
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  2. Yu. G. Suzdaltseva
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  3. V. V. Burunova
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  4. P. A. Karalkin
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  5. A. Yu. Lupatov
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  6. K. N. Yarygin
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Corresponding author

Correspondence to I. V. Vakhrushev.

Additional information

Translated from Kletochnye Tehnologii v Biologii i Medicine, No. 1, pp. 55-60, January, 2010

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Vakhrushev, I.V., Suzdaltseva, Y.G., Burunova, V.V. et al. Mesenchymal Cells of the Deciduous Tooth Pulp: Cytophenotype and Initial Evaluation of Possibility of Their Use in Bone Tissue Engineering. Bull Exp Biol Med 149, 161–165 (2010). https://doi.org/10.1007/s10517-010-0897-0

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  • DOI: https://doi.org/10.1007/s10517-010-0897-0

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