The effects of semax on anticoagulant, fi brinolytic, and platelet components of the anticoagulation system were studied on albino rats under conditions of acute and chronic immobilization stress. Semax exhibited a protective antistress effect after repeated intranasal administration under conditions of hypercoagulation developing in response to immobilization stress of different degree. The effect manifested in stimulation of the anticoagulation system.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 149, No. 1, pp. 49–52, January, 2010
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Grigorjeva, M.E., Lyapina, L.A. Anticoagulation and Antiplatelet Effects of Semax under Conditions of Acute and Chronic Immobilization Stress. Bull Exp Biol Med 149, 44–46 (2010). https://doi.org/10.1007/s10517-010-0871-x
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DOI: https://doi.org/10.1007/s10517-010-0871-x