Skip to main content

Advertisement

Log in

Morphological and Functional State of Major Salivary Glands under Conditions of Aluminum Chloride Excess in Drinking Water

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Morphology and function of the major salivary glands were studied in 50 albino rats drinking water supplemented with aluminum chloride for 2 weeks. Against the background of normal gland appearance, the salivation function and the composition of the saliva were changed: the concentrations of sodium and calcium ions and α-amylase activity were reduced. In parallel, cholesterol content was increased by 54%.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. O. P. Bol’shakov, N. G. Neznanov, and R. V. Babakhanyan, Kach. Klin. Pract., No. 1, 24-28 (2002).

    Google Scholar 

  2. G. M. Vishnevskaya and T. M. Lyashevskaya, Lab. Delo., No. 7, 444-446 (1976).

    Google Scholar 

  3. A. B. Denisov, Saliva. Salivary Glands [In Russian], Moscow (2006), p. 63.

  4. M. I. Nekipelov. Microelements in Medicine, Eds. M. G. Kolomiytsev, G. D. Gabovich [In Russian], Moscow (1970), pp. 133-136.

  5. Guidelines for Preclinical Assessment of the Safety of Pharmacological Agent (GLP) [In Russian], RD -- 64-126-91. Moscow (1992).

  6. C. L. Crocker, Am. J. Med. Technol., 33, No. 5, 361-365 (1967).

    CAS  PubMed  Google Scholar 

  7. J. Fischer and J. Tovarek, Clin. Chem., 31, 166 (1975).

    Google Scholar 

  8. A. Graczyk, K. Radomska, and M. Dlugaszek, Synergizm i antagonizm między biopierwiastkami i metalami toksycznymi. Ochrona Srodowiska i Zasobow Naturalych nr 18. Instytut Ochrony Srodowiska. Warszawa, No. 18, 39-45 (1999).

  9. H. O. Hellstrom, B. Mjoberg, H. Mallmin, and K. Michaelsson, Osteoporos. Int., 16, No. 12, 1982-1988 (2005).

    Article  PubMed  Google Scholar 

  10. E. Holzle and and O. Braun-Falco, Br. J. Dermatol., 110, No. 4, 399-403 (1984).

    Article  CAS  PubMed  Google Scholar 

  11. S. Ilca, Zschr. Ges. Inn. Med., B. 17, H2. S. 83 (1962).

  12. G. N. Krasovskii, L. Y. Vasukovich, and O. G. Chariev, Environ. Health Perspect., 30, 47-51 (1979).

    Article  CAS  PubMed  Google Scholar 

  13. S. Reitman and S. Frankel, Am. J. Clin. Pathol., 28, No. 1, 56-63 (1957).

    CAS  PubMed  Google Scholar 

  14. R. J. Ward and Y. Zhang, and R. R. Crichton, J. Inorg. Biochem., 87, Nos. 1-2, 9-14 (2001).

    Article  CAS  PubMed  Google Scholar 

  15. R. Viestra and A. Haug, Biochem. Biophys. Res. Commun., 84, No. 1, 138-143 (1978).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A. B. Denisov.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 148, No. 12, pp. 703-706, December, 2009

Rights and permissions

Reprints and permissions

About this article

Cite this article

Denisov, A.B. Morphological and Functional State of Major Salivary Glands under Conditions of Aluminum Chloride Excess in Drinking Water. Bull Exp Biol Med 148, 940–942 (2009). https://doi.org/10.1007/s10517-010-0857-8

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-010-0857-8

Key Words

Navigation