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Structure and Functional Loading of Cerebral Arterial Smooth Myocyte Population

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Bulletin of Experimental Biology and Medicine Aims and scope

The cerebral arterial smooth myocytes of dogs with experimental hypertension (n=12), its correction (n=10), and of intact dogs (n=8) were studied. The structure of myocyte population changed under conditions of vascular wall hyperfunction: the size of the cytoplasm and nuclei, DNA content in the nuclei, mitotic activity, and percentage of binuclear forms increased. Thickening of the tunica media in intraorgan arteries was caused by such cytological mechanisms as leiomyocyte hyperplasia and hypertrophy. The cells shrank after elimination of hypertension, while vascular polyploidy persisted.

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References

  1. V. Ya. Belov, M. E. Kogan, and T. A. Leontyeva, Tsitologiya, 117, No. 11, 1332-1338 (1975).

    Google Scholar 

  2. N. A. Belokon’ and V. P. Podzolkov, Congenital Heart Diseases [in Russian], Moscow (1991).

  3. A. N. Gansburgsky and A. V. Pavlov, Ontogenez, 24, No. 6, 79-82 (1993).

    Google Scholar 

  4. A. N. Gansburgsky and A. V. Pavlov, Morfologiya, 113, No. 2, 66-70 (1998).

    Google Scholar 

  5. A. N. Gansburgsky and A. V. Jaltzev, Byull. Eksp. Biol. Med., 138, No. 11, 589-591 (2004).

    Google Scholar 

  6. A. L. Zashikhin and Ya. Selin, Visceral Smooth Muscle Tissue [in Russian], Archangelsk-Umeo (2001).

  7. D. S. Sarkisov, M. A. Pal'tsev, and N. K. Khitrov, Common Human Pathology [in Russian], Moscow (1997).

  8. S. V. Shormanov and A. V. Jaltzev, Byull. Eksp. Biol. Med., 123, No. 5, 591-593 (1997).

    Article  CAS  Google Scholar 

  9. S. V. Shormanov A. V. Jaltzev, I. S. Shormanov, and S. V. Kulikov, Morfologiya, 131, No. 1, 44-49 (2007).

    CAS  Google Scholar 

  10. A. V. Jaltzev, Ibid., 122, No. 6, 34-37 (2002).

    Google Scholar 

  11. V. Ya. Brodsky and I. V. Uryvaeva, Genome Multiplication in Growth and Development, Cambridge (1985).

  12. H. T. Patel, A. Madani, and Y. M. Paris, Pediatr. Cardiol., 22, No. 1, 53-57 (2001).

    Article  CAS  PubMed  Google Scholar 

  13. P. S. Rao, Semil. Nephrol., 15, No. 2, 87-105 (1995).

    CAS  Google Scholar 

  14. H. Veno, P. Kanellaris, and A. Agrotis, Hypertension, 36, No. 1, 89-96 (2000).

    Google Scholar 

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Authors and Affiliations

  1. Department of Histology, Cytology, and Embryology, Department of Pathology with a Course of Section, Yaroslavl State Medical Academy, the Russian Ministry of Public Health, Yaroslavl, Russia

    A. N. Gansburgsky & A. V. Jaltzev

Authors
  1. A. N. Gansburgsky
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  2. A. V. Jaltzev
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Correspondence to A. N. Gansburgsky.

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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 147, No. 6, pp. 708-711, June, 2009

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Gansburgsky, A.N., Jaltzev, A.V. Structure and Functional Loading of Cerebral Arterial Smooth Myocyte Population. Bull Exp Biol Med 147, 764–767 (2009). https://doi.org/10.1007/s10517-009-0613-0

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  • DOI: https://doi.org/10.1007/s10517-009-0613-0

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