Examination of fluorescent Ca2+-responses to stimulation by ionotropic glutamate receptor agonists in rat cerebral cortex slices, preconditioned with hypobaric hypoxia, has demonstrated different time course for up-regulation of their Ca2+-conductivity and for stimulation of the consequent binding of the Ca2+ which entered the cell. The evident result is the development of AMPA-mediated moderate increase of intracellular Ca2+.
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Translated from Byulleten’ Experimental’noi Biologii i Meditsiny, Vol. 147, No 2, pp. 144–147, February, 2009
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Semenov, D.G., Belyakov, A.V. & Samoilov, M.O. Moderate Hypobaric Hypoxia Modifies Ca2+-Mediated Glutamatergic Signal Transduction in Rat Cerebral Cortex. Bull Exp Biol Med 147, 185–188 (2009). https://doi.org/10.1007/s10517-009-0467-5
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DOI: https://doi.org/10.1007/s10517-009-0467-5