Effect of α-tocopherol (vitamin E) periodical administration on heart rhythm regulation was investigated in outbred white rats. α-Tocopherol administration to males was followed by reduction of sympathetic neural influence on heart rhythm and also by the increase of the number of individuals with high activity of autonomic regulation loop. In female rats α-tocopherol administration modulates the activity of humoral control circuit and promotes heart rate reduction, however upon that the percent of females with high centralization of heart rate regulation was increased.
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References
R. M. Bayevsky, G. G. Ivanov, L. V. Chireikin, et al., Vestn. Arythmol., No. 24, 1–23 (2001).
T. S. Balashova, N. K. Khitrov, and A. M. Gerasimov, Ross. Fiziol. ZZhurn., 76, No. 10, 1312–1316 (1990).
L. M. Belkina, V. L. Lakomkin, A. G. Zhukova, et al., Bull. Exp. Biol., 138, No. 9, 250–253 (2004).
O. S. Belokoneva and S. V. Zaitsev, Biokhimiia, 58, No. 11, 1685–1708 (1993).
E. L. Vishnevsky, A. E. Vishnevskaya, E. I. Shabelnikova, et al., Bull. Exp. Biol., 138, No. 11, 496–498 (2004).
E. V. Kuryanova, V. F. Savin, and D. L.Tepliy, Izv. Vuzov, Sev.-Kavk. Region. Estestvenniye nauki, No. 4, 66–69 (2007).
R. R. Nigmatullina, A. G. Nasyrova, and F. F. Rakhmatulina, Bull. Exp. Biol. Med., 134, No. 7, 40–43 (2002).
D. L. Tepliy, Citologiia, 32, No. 12, 1161–1167 (1990).
D. Manzella, M. Barbieri, E. Ragno, and G. Paolisso, Am. J. Clin. Nutr., 73, No. 6, 1052–1057 (2001).
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Translated from Byulleten’ Experimental’noi Biologii i Meditsiny, Vol. 147, No 2, pp. 130–133, February, 2009
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Kuryanova, E.V. Heart Rate Variability in Outbred White Rats upon Periodical α-Tocopherol Administration. Bull Exp Biol Med 147, 173–176 (2009). https://doi.org/10.1007/s10517-009-0464-8
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DOI: https://doi.org/10.1007/s10517-009-0464-8