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Effects of prenatal and neonatal cadmium intoxication on the intensity of lipid peroxidation and activity of glutathione system in progeny of albino rats

  • Biophysics and Biochemistry
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Oral treatment of pregnant or lactating rats with Cd(NO3)2 in a dose of 2 mg/kg increased plasma and erythrocyte levels of MDA and reduced glutathione, activities of glutathione-S-transferase, glutathione reductase, and γ-glutamyl transferase in their 4-month-old progeny. Changes in the function of glutathione system and LPO intensity after cadmium intoxication during the neonatal were less pronounced than after prenatal exposure.

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Authors and Affiliations

  1. Department of Biochemistry and Biophysics, N. G. Chernyshevsky Saratov State University, Saratov, Russia

    O. V. Slyuzova, E. V. Stepanova, A. D. Temraleeva, R. A. Kireev & V. V. Ignatov

Authors
  1. O. V. Slyuzova
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  2. E. V. Stepanova
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  3. A. D. Temraleeva
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  4. R. A. Kireev
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  5. V. V. Ignatov
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Corresponding author

Correspondence to O. V. Slyuzova.

Additional information

Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 146, No. 7, pp. 46–49, July, 2008

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Slyuzova, O.V., Stepanova, E.V., Temraleeva, A.D. et al. Effects of prenatal and neonatal cadmium intoxication on the intensity of lipid peroxidation and activity of glutathione system in progeny of albino rats. Bull Exp Biol Med 146, 41–44 (2008). https://doi.org/10.1007/s10517-008-0230-3

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  • DOI: https://doi.org/10.1007/s10517-008-0230-3

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