Abstract
Intracerebroventricular injection of recombinant human interferon-2α (100–500 U/rat) decreased the mean effective dose of corasol inducing clonic convulsions in 50% kindled Wistar rats. This effect was more pronounced in delayed periods of kindling and was accompanied by enhancement of epileptiform signs on EEG.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 7, pp. 11–14, July, 2007
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Kresyun, V.I., Kobolev, E.V., Smirnov, I.V. et al. Effects interferon-2α on seizures in corasol-induced kindling. Bull Exp Biol Med 144, 8–11 (2007). https://doi.org/10.1007/s10517-007-0240-6
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DOI: https://doi.org/10.1007/s10517-007-0240-6