Abstract
Binding of FITC-labeled lectins to lymphocytes from intact mice and mice with transplanted Ehrlich carcinoma and CaO-1 ovarian carcinoma was studied by flow cytofluorometry. Specific binding of lectins by mannose and N-acetylgalactosamine was demonstrated. Lectin binding to lymphocytes from animals with tumors decreased by more than 50% in comparison with intact animals. Changed protein glycosylation during tumor growth is specific and differs for tumors of different origin.
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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 140, No. 10, pp. 446–449, October, 2005
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Sitdikova, S.M., Amandzholov, B.S., Kiselevskii, M.V. et al. Lectin Binding to Mouse Blood Lymphocytes during Tumor Growth. Bull Exp Biol Med 140, 445–448 (2005). https://doi.org/10.1007/s10517-005-0515-8
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DOI: https://doi.org/10.1007/s10517-005-0515-8