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Heart resistance to oxidative stress in rats of different genetic strains

  • General Pathology and Pathological Physiology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

In August rats reperfusion after regional myocardial ischemia in situ or intracoronary administration of hydrogen peroxide less significantly suppressed contractile activity of the heart compared to Wistar rats. Activities of catalase and superoxide dismutase in the myocardium during reperfusion remained unchanged in August rats. In Wistar rats a profound inhibition of cardiac function was accompanied by a decrease in enzyme activity.

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Authors and Affiliations

  1. Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Russia

    L. M. Belkina, V. L. Lakomkin, A. G. Zhukova, T. N. Kirillina, V. A. Saltykova, T. G. Sazontova & V. I. Kapel’ko

  2. Russian Cardiology Research-and-Production Center, Russian Ministry of Health, Moscow

    L. M. Belkina, V. L. Lakomkin, A. G. Zhukova, T. N. Kirillina, V. A. Saltykova, T. G. Sazontova & V. I. Kapel’ko

Authors
  1. L. M. Belkina
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  2. V. L. Lakomkin
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  3. A. G. Zhukova
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  4. T. N. Kirillina
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  5. V. A. Saltykova
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  6. T. G. Sazontova
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  7. V. I. Kapel’ko
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Corresponding author

Correspondence to L. M. Belkina.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 138, No. 9, pp. 250–253, September, 2004

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Belkina, L.M., Lakomkin, V.L., Zhukova, A.G. et al. Heart resistance to oxidative stress in rats of different genetic strains. Bull Exp Biol Med 138, 219–222 (2004). https://doi.org/10.1007/s10517-005-0003-1

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  • DOI: https://doi.org/10.1007/s10517-005-0003-1

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