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The Association Between Homophily on Illicit Drug Use and PrEP Conversations Among Latino Men Who Have Sex with Men Friends: A Dyadic Network and Spatially Explicit Study

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Abstract

Despite the wide availability of PrEP, Latino men who have sex with men (LMSM) continue to experience access barriers. Novel HIV prevention research strategies to increase PrEP uptake and adherence among the high incidence populations, such as LMSM who misuse drugs, include social network analyses. This study identified the associations of drug use homophily within LMSM friendship networks and PrEP promotion conversations and described the physical overlap between geographic drug risk areas with conversations of PrEP promotion. Respondent-driven sampling was used to recruit 10 sociocentric networks. Quadratic assignment procedure (QAP) correlations and multiple regression QAPs were used to identify influences of drug use homophily, and geocoding and visualizations to describe drug use polygons and PrEP conversations. Friendship relationships in which both friends used cocaine or marijuana were more likely to report PrEP-related conversations in the past six months. The likelihood of talking about PrEP in the next six months was higher among dyads with cocaine use homophily and ecstasy use homophily, while lower among dyads with marijuana use homophily. Participants reported using marijuana and cocaine throughout Miami-Dade County while ecstasy polygons were mostly in urban areas. The majority of drug polygons associated with PrEP conversations were located in north and central Miami. Future interventions can consider enrolling entire sociocentric friendship groups, configuring friendship networks to connect those without PrEP information to those with information, and incorporating peer leaders.

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Authors and Affiliations

  1. Department of Public Health Sciences, University of Miami Miller School of Medicine, 1120 NW 14th St. STE 1006, Miami, FL, 33136, USA

    Mariano Kanamori, Cho-Hee Shrader, Ariana Johnson, Juan Arroyo-Flores & Edda Rodriguez

  2. Department of Sociology, University of South Florida, Tampa, FL, USA

    John Skvoretz

  3. Latinos Salud, Wilton Manors, FL, USA

    Stephen Fallon & Victor Gonzalez

  4. Department of Psychology, University of Miami, Coral Gables, FL, USA

    Steven Safren

  5. Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AK, USA

    Mark Williams

  6. Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA

    Susanne Doblecki-Lewis

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  1. Mariano Kanamori
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  2. Cho-Hee Shrader
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Correspondence to Mariano Kanamori.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by the University of Miami’s Institutional Review Board (IRB # 20180284).

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Kanamori, M., Shrader, CH., Johnson, A. et al. The Association Between Homophily on Illicit Drug Use and PrEP Conversations Among Latino Men Who Have Sex with Men Friends: A Dyadic Network and Spatially Explicit Study. Arch Sex Behav 51, 2485–2495 (2022). https://doi.org/10.1007/s10508-021-02131-4

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